The field of bioseparation, and biochromatography in particular, is advancing very rapidly as our knowledge of the properties of molecules and atomic forces increases. This volume covers the basic principles of biochromatography in detail. It assesses different techniques and includes a large number of applications, providing the reader with a multidisciplinary perspective that gives the insight to master the many chromatographic methods. Biochromatography: Theory and Practice is a valuable tool for graduate and research scientists, technicians, engineers and teachers in a range of fields including biochemistry, biotechnology, biorecognition and chromatography.

The field of bioseparation, and biochromatography in particular, is advancing very rapidly as our knowledge of the molecular properties of molecules and atomic forces increases. In biochromatography, an empirical approach has usually been used with methods quickly being condemned and an alternative solution sought. A good theoretical understanding of the mechanisms involved will lead to a more rational design of the biochromatographic separation methods which, in turn, enables these simple chromatographic methods to emerge as powerful analytical tools.
This volume covers the basic principles of biochromatography in detail. Different techniques are assessed and a large number of applications are included, providing the reader with a multidisciplinary perspective that will give them the insight to master the many chromatographic methods.
This book will be a valuable tool for graduate and research scientists, technicians, engineers and teachers in a range of fields including biochemistry, biotechnology, biorecognition and chromatography.

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This volume contains the papers and reports presented at the First International Conference on Dye-Protein Interaction, held 24-28 July 1988 at the University of Compiegne, France. This was the first international meeting dealing entirely with dye-protein interaction. The major focus of the conference was on the better understanding of the mechanism of interaction of proteins with different triazine dyes and the synthesis of novel structural dyes having good biomimetic activities. The potentials and limits of their use in biotechnology, mainly for purification, were stressed. Current contributions in developing dye-based affinity methods were highlighted in such areas as affinity partition, affinity precipitation and new support matrices for efficient affinity chromatography, etc. The interrelation between metal chelates and dyes in terms of their interactions with proteins was underlined. It is our belief that this proceedings volume will be a stimulus for broad and creative applications of dye affinity concepts in many fields of biomedical research and biotechnology. for understanding the In addition, a discussion session emphasised the necessity toxicological aspects of these dyes, their fragments and their metabolites. This helped to trigger plans for future work, and this topic will be one of the priorities in a future meeting on dye-protein interactions. C. R. The help of the International Scientific Committee, which included Drs Lowe (UK), G. KopperschHiger (GDR) , E. Stellwagen (USA), D. Thomas (France), G. Birkenmeier (GDR), S. Rajgopal-Narayan (USA), J. P. Dandeu (France), D. Muller (France) and E. Dellacherie (France), in organising this meeting is gratefully acknowledged.