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There have been many advances in the field of gastrointestinal pa
thology which are of considerable clinical significance during the
13 years since the last publication of a volume of Current Topics
in Pathology devoted to this subject. Many have arisen from the app
lication of new techniques of histochemistry, immunocytochemi stry,
quantitative morphometry and molecular and cell biology to
gastrointestinal diseases, but some, notably the recognition of the
association of Campylobaeter pylori with the commonest type of
chronic gastritis, have been achieved using such long established
'routine' histological procedures that one wonders how their
signifi cance had escaped recognition for so long. The topics
covered in this volume have been selected because they present
advances of relevance to the diagnostic clinical pathologist.
However, they re present the personal selection of the editor, and
are in no way exhaustive. Many other examples of progress in our
understanding of the pathophysiology of gastrointestinal diseases
have been omit ted, either because of the confines of space or
because they have been well reviewed recently in other
publications. Most of the workload of the practising
gastrointestinal patholo gist involves the diagnosis and assessment
either of inflammation or of neoplasia in the alimentary tract, and
this is reflected in the topics presented in this book."
The "Europe against Cancer" programme has, from its inception,
emphasised the key role which general practitioners must play in
the actions necessary to achieve its aim of reducing the incidence
and the mortality from cancer in the European Community. General
practitioners, because of their day-to-day direct and continuing
contact with patients, playa role not only in primary prevention
and education of patients, but also in motivating their patients to
accept secondary prevention and screening, some of it carried out
by general practitioners themselves. These preventive activities
are in addi tion to their traditional role in the care and
management of patients with cancer at home, and increasingly, their
role in active treatment. In view of the importance of the general
practitioner in the "Europe against Cancer" programme, the European
Commission, with a view to providing general practitioners with
up-to-date useful information, has sponsored the production of this
series of publi cations on organbased cancers, especially written
for general practitioners. Regis Malbois Advisor in charge of the
"Europe against Cancer" programme Commission of the European
Communities Brussels Preface Colorectal cancer is the second most
common cause of death from malignant disease with a high incidence
in many European countries. This book is part of a series of pub
lications on major cancer diseases designed for the European family
doctor. It is pub lished by the Commission of the European
Communities within the context of the Eu rope Against Cancer
Programme.
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