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This comprehensive treatise on the reticuloendothelial system is a
project jointly shared by individual members of the
Reticuloendothelial (RE) Society and bio- medical scientists in
general who are interested in the intricate system of cells and
molecular moieties derived from those cells that constitute the
RES. It may now be more fashionable in some quarters to consider
these cells as part of what is called the mononuc1ear phagocytic
system or the lymphoreticular system. Nevertheless, because of
historical developments and current interest in the subject by
investigators from many diverse areas, it seems advantageous to
present in one comprehensive treatise current information and
knowledge con- cerning basic aspects of the RES, such as
morphology, biochemistry, phylogeny and ontogeny, physiology, and
pharmacology, as well as c1inical areas inc1uding immunopathology,
cancer, infectious diseases, allergy, and hypersensitivity. It is
anticipated that, by presenting information concerning these
apparently het- erogeneous topics under the unifying umbrella of
the RES, attention will be focused on the similarities as well as
interactions among the cell types constitut- ing the RES from the
viewpoint of various disciplines. The treatise editors and their
editorial board, consisting predominantly of the editors of
individual vol- umes, are extremely grateful for the enthusiastic
cooperation and enormous task undertaken by members of the
biomedical community in general and especially by members of the
American as well as European and Japanese Reticuloen- dothelial
Societies.
The Reticuloendothelial (RE) Society, which is concerned with
advancement of knowledge concerning the many diverse functions of
RE cells, organizes national and international meetings and
publishes a scientific journal. The VIII International Congress of
theRE Society was held in Jerusalem, Israel, June 18-23, 1978. The
Congress had as its scientific objective a wide range of sub jects
concerning the RE System, especially as related to macro phage
function and interaction with lymphocytes. Emphasis of the Congress
was placed on the nature and function of macrophages and other
cells of the RE System with reference to immune responses,
anti-infectious activity, tumor immunity, autoimmunity, and trans
plant rejection. The secretion of soluble factors by macrophages
and lymphocytes and the mode of action of these factors on other
cells was stressed. During the Congress some discussion was
entertained concerning the controversy as to what constitutes the
"RE System" per se. Some investigators feel that the phagocytic
activity of ~~crophages is the most important aspect of the RE
System playing also a major role in many parameters of immunity.
Mononuclear phagocytes include tissue macrophages as well as cir
culating monocytes and their precursors. Although phagocytosis is a
major functional activity of these cells, it is only one of several
activities.
This comprehensive treatise on the reticuloendothelial system is a
project jointly shared by individual members of the
Reticuloendothelial (RE) Society and bio medical scientists in
general who are interested in the intricate system of cells and
molecular moieties derived from those cells which constitute the
RES. It may now be more fashionable in some quarters to consider
these cells as part of what is called the mononuclear phagocytic
system or the lymphoreticular sys tem. Nevertheless, because of
historical developments and current interest in the subject by
investigators from many diverse areas, it seems advantageous to
present in one comprehensive treatise current information and
knowledge con cerning basic aspects of the RES, such as morphology,
biochemistry, phylogeny and ontogeny, physiology, and pharmacology
as well as clinical areas including immunopathology, cancer,
infectious diseases, allergy, and hypersensitivity. It is
anticipated that, by presenting information concerning these
apparently het erogeneous topics under the unifying umbrella of the
RES, attention will be focused on the similarities as well as
interactions among the cell types constitut ing the RES from the
viewpoint of various disciplines. The treatise editors and their
editorial board, consisting predominantly of the editors of
individual vol and enormous task umes, are extremely grateful for
the enthusiastic cooperation undertaken by members of the
biomedical community in general and especially and Japanese
Reticuloen by members of the American as well as European dothelial
Societies.
The Reticuloendothelial (RE) Society, which is concerned with advd
cement of knowledge concerning the many diverse functions of RE
cells, organizes national and international meetings and publishes
a scientific journal. The VIII International Congress of the RE
Society was held in Jerusalem, Israel, June 18-23, 1978. The
Congress had as its scientific objec, tive a wide range of sub
jects concerning the RE System, especially as related to macro
phage function and interaction with lymphocytes. Emphasis of the
Congress was placed on the nature and function of macrophages and
other cells of the RE System with reference to immune responses,
anti-infectious activity, tumor immunity, autoimmunity, and trans
plant rejection. The secretion of soluble factors by rnacrophages
and lymphocytes and the mode of action of these factors on other
cells was stressed. During the Congress some discussion was
entertained concerning the controversy as to what constitutes the
"RE System" per se. Some investigators feel that the phagocytic
activity of rnacrophages is the most important aspect of the RE
System playing also a major role in many parameters of immunity.
Mononuclear phagocytes include tissue rnacrophages as well as cir
culating monocytes and their precursors. Although phagocytosis is a
major functional activity of these cells, it is only one of several
activities."
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