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The tumor environment is a dynamic network that includes cancer
cells, immune cells, fibroblasts, endothelial cells, extracellular
matrix, cytokines and receptors. The aim of this book is to
summarize the role of these components, especially immune cells, in
tumor suppression and/or progression and describe in detail why
tumor cells can survive and spread in spite of the antitumor
response of immune cells. Since immunotherapy is an attractive
approach to cancer therapy, this book also provides information on
the two main strategies: monoclonal antibodies and adaptive T cell
immunotherapy, with a focus on recent human clinical trials. The
book provides a state-of-the-art, comprehensive overview of immune
cells in cancer and is an indispensable resource for scientists and
medical doctors working and/or lecturing in the field of cancer
research and immunology.
Now, it its second edition, this book summarizes the role of immune
cells in tumor suppression and progression. It describes in detail
why tumor cells can survive and spread in spite of the antitumor
response of immune cells. Since immunotherapy is an attractive
approach to cancer therapy, this book also provides information on
the two main strategies: monoclonal antibodies and adaptive T cell
immunotherapy, with a focus on recent human clinical trials. A
newly added chapter also focuses on the role of Natural Killer
cells in tumor progression. The book provides a state-of-the-art,
comprehensive overview of immune cells in cancer and is an
indispensable resource for researchers and practitioners working or
lecturing in the field of cancer research and immunology.
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