Integrative Omics: Concepts, Methodology and Applications provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference includes a range of chapters in a systemic ‘step by step’ manner, which begins with the basic concepts from Omic to Multi Integrative Omics approaches, followed by their full range of approaches, applications, emerging trends, and future trends. All key areas of Omics are covered including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics as well as omics technology policy and society research. Integrative Omics: Concepts, Methodology and Applications highlights the recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science.  The book bridges the gap between biological sciences, physical sciences, computer science, statistics, data science, information technology and mathematics by presenting content specifically dedicated to mathematical models of biological systems.

The present study was carried out to investigate Monochoria vaginalis P. roots pharmacognostically and phytochemically and also to evaluate same for Analgesic activity. The detailed morphology of Monochoria vaginalis P roots was carried out to support proper identification of drug selected for investigation. Various proximate values for the roots of Monochoria vaginalis P. were performed. Qualitative chemical examinations of various extracts revealed the presence of Alkaloids, Phenols, Carbohydrates, Glycosides, Tannin, Flavonoids. Further, TLC studies of total alcoholic and chloroform fraction were carried out to substantiate the presence of Phytoconstituents. An attempt was also made to isolate compounds by Column chromatography and further characterized the isolated compounds by physical parameters, chemical tests, TLC and by spectral studies such as, UV, FT-IR, 1H-NMR and LC-MS. The total ethanolic extract, chloroform fraction and aqueous extract of Monochoria vaginalis P. was evaluated for Analgesic activity in mice and the extract showed significant analgesic activity at all tested levels by Tail immersion and Eddy's hot plate methods.

The present work focuses on the development of hydrodynamically balanced delivery system of Aceclofenac as a single-unit floating Tablet. Floating effervescent tablets were formulated by various materials like. HPMC, K4M, K 15M, psyllium husk, swelling agent as crospovidone and micro crystalline cellulose and gas generating agent like sodium bicarbonate and citric acid. Floating non effervescent tablets were prepared by polypropylene foam powder and different matrix forming polymers. The prepared floating tablets were evaluated for various Parameter. The formulation was optimized on the basis of in vitro buoyancy and in vitro release By fitting the data into different models, we concluded that the mechanism of release of Aceclofenac from the floating tablet was anomalous diffusion transport and follows zero order kinetics, Stability studies revealed that formulations were stable when stored at different temperatures and the values were within permissible limits. X ray imaging studies results showed that tablet was float more than 8 h in gastric region of the Albino rabbits.