This book consists of eighteen articles in the area of `Combinatorial Matrix Theory' and `Generalized Inverses of Matrices'. Original research and expository articles presented in this publication are written by leading Mathematicians and Statisticians working in these areas. The articles contained herein are on the following general topics: `matrices in graph theory', `generalized inverses of matrices', `matrix methods in statistics' and `magic squares'. In the area of matrices and graphs, speci_c topics addressed in this volume include energy of graphs, q-analog, immanants of matrices and graph realization of product of adjacency matrices. Topics in the book from `Matrix Methods in Statistics' are, for example, the analysis of BLUE via eigenvalues of covariance matrix, copulas, error orthogonal model, and orthogonal projectors in the linear regression models. Moore-Penrose inverse of perturbed operators, reverse order law in the case of inde_nite inner product space, approximation numbers, condition numbers, idempotent matrices, semiring of nonnegative matrices, regular matrices over incline and partial order of matrices are the topics addressed under the area of theory of generalized inverses. In addition to the above traditional topics and a report on CMTGIM 2012 as an appendix, we have an article on old magic squares from India.

Circulation of blood is vital for the survival of vertebrates, including man. Mainly, it plays an important role in carrying food nutrients and oxygen to every tissue and organ and in removing all waste products and carbon dioxide. Any imbalance in the hemostatic and cardiovascular systems can lead to death and severe debility. A number of animals have developed mechanisms to target these systems and exploit the vulnerability. In some species (for example, snakes), such mechanisms are used to immobilize and kill the victim/prey, whereas in others (for example, insects, such as leaches, mosquitoes and ticks), they are used to provide a continuous supply of blood. These mechanisms include, but are not limited to, procoagulant and anticoagulant actions that affect the coagulation cascade and platelet aggregation, as well as altering vasodilatory responses. In all these various animals, these mechanisms have evolved to perfection over millions of years to support their survival. In last 3-4 decades, due to the efforts of scientists from various backgrounds including biology, protein chemistry, molecular biology, pharmacology, hematology, and structural biology, significant progress in understanding the structure-function relationships, as well as the mechanism of action have been made in a number of exogenous factors that affect blood coagulation, platelet aggregation and vasodilation from various animals. These exogenous factors have contributed significantly to the development of research tools as well as providing new therapeutic agents. With the increase average age of the population coupled with changes in life style in recent years, there has been a significant increase in cardiovascular and hematological disorders. Thus scientists in both academic institutions as well as the pharmaceutical industry are developing better therapeutic agents to improve the quality of life. This impetus has lead to the search for novel agents from various sources that interfere with cardiovascular and hematalogical processes. Although at first glance exogenous factors appear to function as 'villains', several life-saving drugs have been developed based upon these factors. Such drugs or drug leads include those that inhibit the angiotensin converting enzymes (Captopril and Enalapril), that block platelet receptors (Eptifibatide and Tirofiban), or that digest thrombotic plugs (Alfimeprase and bat plasminogen activator) to name a few. Several new and exciting success stories are currently unfolding. In this book, recent studies on some of the exogenous factors that play crucial roles in cardiovascular and hematological disorders are reviewed in order to consolidate the efforts in this area of research and to recruit new, talented researchers. The 25-30 review chapters, each written by experts in their field, compiled herein are devoted to exogenous factors affecting platelet aggregation, anticoagulant and procoagulant proteins, fibrinolytic proteins and hypotensive agents (For details see, Contents of the Book). This book is intended to help to create elevated awareness and enthusiasm in the field of exogenous factors. I believe that this book will provide greater impetus to the search for novel proteins based on naturally occurring exogenous factors. This will be the first book dealing extensively with exogenous factors in the last 25 years. The book will provide a ready reference to the different approaches used to solve complex problems in protein chemistry and pharmacology of exogenous factors. The book will update our understanding of the structure-function relationships and mechanisms of action of exogenous factors and provide great insights into future directions for solving the remaining challenges.

Carbon Nanomaterials-Based Sensors: Emerging Research Trends in Devices and Applications covers the most recent research and design trends for carbon nanomaterials-based sensors for a variety of applications, including clinical and environmental uses, and more. Carbon nanomaterials-based sensors can be used with high sensitivity, stability and accuracy compared to other techniques. Written by experts in their given fields from around the world, this book helps researchers solve the particular challenges they face when developing new types of sensors. It instructs how to make sensitive, selective, robust, fast-response and stable carbon nanomaterial-based sensors, as well as how to utilize them in real life.

Functionalized Nanomaterial-Based Electrochemical Sensors: Principles, Fabrication Methods, and Applications provides a comprehensive overview of materials, functionalized interfaces, fabrication strategies and application areas. Special attention is given to the remaining challenges and opportunities for commercial realization of functionalized nanomaterial-based electrochemical sensors. An assortment of nanomaterials has been investigated for their incorporation into electrochemical sensors. For example, carbon- based nanomaterials (carbon nanotube, graphene and carbon fiber), noble metals (Au, Ag and Pt), polymers (nafion, polypyrrole) and non-noble metal oxides (Fe2O3, NiO, and Co3O4). The most relevant materials are discussed in the book with an emphasis on their evaluation of their realization in commercial applications. Application areas touched on include the environment, food and medicine industries. Health, safety and regulation considerations are touched on, along with economic and commercialization trends.

Circulation of blood is vital for the survival of vertebrates, including man. Mainly, it plays an important role in carrying food nutrients and oxygen to every tissue and organ and in removing all waste products and carbon dioxide. Any imbalance in the hemostatic and cardiovascular systems can lead to death and severe debility. A number of animals have developed mechanisms to target these systems and exploit the vulnerability. In some species (for example, snakes), such mechanisms are used to immobilize and kill the victim/prey, whereas in others (for example, insects, such as leaches, mosquitoes and ticks), they are used to provide a continuous supply of blood. These mechanisms include, but are not limited to, procoagulant and anticoagulant actions that affect the coagulation cascade and platelet aggregation, as well as altering vasodilatory responses. In all these various animals, these mechanisms have evolved to perfection over millions of years to support their survival. In last 3-4 decades, due to the efforts of scientists from various backgrounds including biology, protein chemistry, molecular biology, pharmacology, hematology, and structural biology, significant progress in understanding the structure-function relationships, as well as the mechanism of action have been made in a number of exogenous factors that affect blood coagulation, platelet aggregation and vasodilation from various animals. These exogenous factors have contributed significantly to the development of research tools as well as providing new therapeutic agents. With the increase average age of the population coupled with changes in life style in recent years, there has been a significant increase in cardiovascular and hematological disorders. Thus scientists in both academic institutions as well as the pharmaceutical industry are developing better therapeutic agents to improve the quality of life. This impetus has lead to the search for novel agents from various sources that interfere with cardiovascular and hematalogical processes. Although at first glance exogenous factors appear to function as 'villains', several life-saving drugs have been developed based upon these factors. Such drugs or drug leads include those that inhibit the angiotensin converting enzymes (Captopril and Enalapril), that block platelet receptors (Eptifibatide and Tirofiban), or that digest thrombotic plugs (Alfimeprase and bat plasminogen activator) to name a few. Several new and exciting success stories are currently unfolding. In this book, recent studies on some of the exogenous factors that play crucial roles in cardiovascular and hematological disorders are reviewed in order to consolidate the efforts in this area of research and to recruit new, talented researchers. The 25-30 review chapters, each written by experts in their field, compiled herein are devoted to exogenous factors affecting platelet aggregation, anticoagulant and procoagulant proteins, fibrinolytic proteins and hypotensive agents (For details see, Contents of the Book). This book is intended to help to create elevated awareness and enthusiasm in the field of exogenous factors. I believe that this book will provide greater impetus to the search for novel proteins based on naturally occurring exogenous factors. This will be the first book dealing extensively with exogenous factors in the last 25 years. The book will provide a ready reference to the different approaches used to solve complex problems in protein chemistry and pharmacology of exogenous factors. The book will update our understanding of the structure-function relationships and mechanisms of action of exogenous factors and provide great insights into future directions for solving the remaining challenges.

This book consists of eighteen articles in the area of `Combinatorial Matrix Theory' and `Generalized Inverses of Matrices'. Original research and expository articles presented in this publication are written by leading Mathematicians and Statisticians working in these areas. The articles contained herein are on the following general topics: `matrices in graph theory', `generalized inverses of matrices', `matrix methods in statistics' and `magic squares'. In the area of matrices and graphs, speci_c topics addressed in this volume include energy of graphs, q-analog, immanants of matrices and graph realization of product of adjacency matrices. Topics in the book from `Matrix Methods in Statistics' are, for example, the analysis of BLUE via eigenvalues of covariance matrix, copulas, error orthogonal model, and orthogonal projectors in the linear regression models. Moore-Penrose inverse of perturbed operators, reverse order law in the case of inde_nite inner product space, approximation numbers, condition numbers, idempotent matrices, semiring of nonnegative matrices, regular matrices over incline and partial order of matrices are the topics addressed under the area of theory of generalized inverses. In addition to the above traditional topics and a report on CMTGIM 2012 as an appendix, we have an article on old magic squares from India.

Surfactant Based Electrochemical Sensors and Biosensors discusses the applications of surfactants for Electrochemical Sensors. Surfactant based electrochemical sensors exhibits elevated sensitivity, selectivity, stability and accuracy as compared to other analytical techniques. The fabricated sensors can be applied for routine analysis in clinical and industrial samples with acceptable recovery. This book covers the emerging research trends and exploitation of surfactants for electrochemical sensor preparation for its applications in various fields such as academia, medicine, industry and monitoring of environmental species. The key focus of this book is to expand scientific research in the field of electrochemistry on surfactant based electrochemical sensors in order to construct highly sensitive devices. Part one presents the characteristics of surfactants and discusses their application for the fabrication of electrochemical sensors and bio sensors. Part two addresses the analysis of toxic chemicals and their quantitative determination and offers surfactant based sensing platforms for environmental modelling. Part three discusses the significance of the analysis of molecules and ions in biological and pharmaceutical sampling. Part four presents new methodologies for the determination of food additives and biological molecules present in food samples. Part 5 explores the Sustainability, Safety and Toxicity Aspects of Surfactant Modified Electrochemical Sensors and Biosensors.

Novel Nanostructured Materials for Electrochemical Bio-sensing Applications presents a detailed overview into the fabrication of electrochemical bio-sensing devices. The book addresses the challenges and opportunities relating to sustainable and biocompatible sensors from food, water and wearable applications to the various nanostructured biocompatible materials required for sensor fabrication. In addition, it explores the connection between nanomaterials and sensors and takes into consideration different and novel approaches such as toxic materials monitoring and health issues correlated with the use of nanomaterials. Users will find exciting insight into innovations in nanostructured electrochemical biosensing. By providing its audience with fundamentals, limitations, challenges, future perspectives and practical sustainability, this book will serve as a reference source researchers and engineers within analytical chemistry and electrochemistry.

This book focuses on research in linear algebra, statistics, matrices, graphs and their applications. Many chapters in the book feature new findings due to applications of matrix and graph methods. The book also discusses rediscoveries of the subject by using new methods. Dedicated to Prof. Calyampudi Radhakrishna Rao (C.R. Rao) who has completed 100 years of legendary life and continues to inspire us all and Prof. Arbind K. Lal who has sadly departed us too early, it has contributions from collaborators, students, colleagues and admirers of Professors Rao and Lal. With many chapters on generalized inverses, matrix analysis, matrices and graphs, applied probability and statistics, and the history of ancient mathematics, this book offers a diverse array of mathematical results, techniques and applications. The book promises to be especially rewarding for readers with an interest in the focus areas of applied linear algebra, probability and statistics.

Describing the importance of surfactants in electrochemical investigations related to biologically and environmentally vital chemicals, this book charts the progression of highly responsive electrochemical sensors using surfactants as a modifying agent in the sensor field. It provides contributed chapters from respected researchers on information concerning the activity of target molecules and electron transfer kinetics arising at the surface of the fabricated sensor materials. Surfactant-based electrochemical sensors are of great interest in the quest to find low-cost, fast and highly responsive sensing devices and one aim of this book is to help improve the competence and knowledge in this newly emerging interdisciplinary research area. Attracting an audience of students, academics, industrialists and engineers, it will interest researchers seeking to use non-toxic sensors in their detection challenges.

The Future Rice Strategy for India presents forward-looking insights toward achieving sustainable development of the rice sector, ensuring future food and nutritional security. As a staple food for many in India, including the economically disadvantaged, there are many concerns that affect the development of rice sector. Facing issues from environmental demands to economic stagnation, access to food, food inflation, and the Food Security Act (demand - supply - distribution of rice) achieving sustainability in production and exports is an important and urgent challenge. Using case studies to illustrate existing and potential issues, challenges and solutions, The Future Rice Strategy for India presents key strategic options while considering the implicit consequences. In addition, the findings enrich the strategy and policy formulation considerations for the role of rice in the country. This multidisciplinary approach features the expertise of rice scientists covering different aspects of rice sector; from breeding to consumer preferences and markets and trade.

The Future Rice Strategy for India presents forward-looking insights toward achieving sustainable development of the rice sector, ensuring future food and nutritional security. As a staple food for many in India, including the economically disadvantaged, there are many concerns that affect the development of rice sector. Facing issues from environmental demands to economic stagnation, access to food, food inflation, and the Food Security Act (demand - supply - distribution of rice) achieving sustainability in production and exports is an important and urgent challenge. Using case studies to illustrate existing and potential issues, challenges and solutions, The Future Rice Strategy for India presents key strategic options while considering the implicit consequences. In addition, the findings enrich the strategy and policy formulation considerations for the role of rice in the country. This multidisciplinary approach features the expertise of rice scientists covering different aspects of rice sector; from breeding to consumer preferences and markets and trade.