|
Showing 1 - 3 of
3 matches in All Departments
This volume explores the epigenetic alterations and their
association with various human cancers. Considering one of human
cancer as an example, individual chapters are focused on defining
the role of epigenetic regulators and underlying mechanisms in
cancer growth and progression. Epigenetic alteration including DNA
methylation, histone modification, nucleosome positioning and
non-coding RNAs expression are involved in a complex network of
regulating expression of oncogenes and tumor suppressor genes and
constitute an important event of the multistep process of
carcinogenesis. Recent advances in the understanding of the
epigenetic regulation and detailed information of these epigenetic
changes in various cancers provide new avenues of advancements in
diagnostics, prognostics, and therapies of this highly fatal
disease.
This volume explores the epigenetic alterations and their
association with various human cancers. Considering one of human
cancer as an example, individual chapters are focused on defining
the role of epigenetic regulators and underlying mechanisms in
cancer growth and progression. Epigenetic alteration including DNA
methylation, histone modification, nucleosome positioning and
non-coding RNAs expression are involved in a complex network of
regulating expression of oncogenes and tumor suppressor genes and
constitute an important event of the multistep process of
carcinogenesis. Recent advances in the understanding of the
epigenetic regulation and detailed information of these epigenetic
changes in various cancers provide new avenues of advancements in
diagnostics, prognostics, and therapies of this highly fatal
disease.
Although there have been tremendous progress in cancer research and
treatment, the mortality caused by this disease is still very high.
Cancer is the leading cause of death worldwide and second leading
cause of death in the United States of America. The book covers
topics including the role of various signalling pathway in
development, regulation of cell fate, tumour angiogenesis, duodenal
neoplasias, breast, colorectal and prostate cancer, cancer
development and progression, microRNA in cancer and epigenetic
regulation of cancer. This book will provide valuable information
for cell biologists, geneticists, cancer biologists, clinicians,
and students involved in various aspects of cell signalling,
regulation of genes and cancer.
|
You may like...
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
|