This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjoegren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases.

The Digestive System in Systemic Autoimmune Diseases, Second Edition, represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases. This volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations. International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico, and South Africa share their knowledge in this detailed volume. The book provides an overview of our current understanding of digestive disorders in the most common systemic autoimmune diseases.

Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.