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Recent major advances in our understanding of modulating protein
functions has led to the development of new methods and algorithms
to predict and decipher how amino acid sequences shape
three-dimensional structures. Protein Design: Methods and
Applications presents the most up-to-date protein design and
engineering strategies so that readers can undertake their own
projects with a maximum chance of success.
The authors present integrated computational approaches that
require various degrees of computational complexity, and the major
accomplishments that have been achieved in the design and
structural characterization of helical peptides and proteins. Other
topics of discussion include: design of structural elementary
motifs, entire proteins, and interfaces of protein complexes, and
of amyloidogenic polypeptides and amyloid inhibitors.
Authoritative and cutting-edge, Protein Design: Methods and
Applications will be of major interest to protein scientists,
biochemists, and all experimentalists selecting the strategy most
adaptable for their design problem.
Protein Design: Methods and Applications presents the most
up-to-date protein design and engineering strategies so that
readers can undertake their own projects with a maximum chance of
success.
The authors present integrated computational approaches that
require various degrees of computational complexity, and the major
accomplishments that have been achieved in the design and
structural characterization of helical peptides and proteins.
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