This book constitutes the proceedings of the 22st International Conference on Embedded Computer Systems: Architectures, Modeling, and Simulation, SAMOS 2021, which took place in July 2022 in Samos, Greece. The 21 full papers presented in this volume were carefully reviewed and selected from 44 submissions. The papers are organized in topics as follows: High level synthesis; memory systems; processor architecture; embedded software systems and beyond; deep learning optimization; extra-functional property estimation; innovative architectures and tools for security; european research projects on digital systems, services, and platforms.

This book constitutes the proceedings of the 21st International Conference on Embedded Computer Systems: Architectures, Modeling, and Simulation, SAMOS 2021, which took place in July 2021. Due to COVID-19 pandemic the conference was held virtually. The 17 full papers presented in this volume were carefully reviewed and selected from 45 submissions. The papers are organized in topics as follows: simulation and design space exploration; the 3Cs - Cache, Cluster and Cloud; heterogeneous SoC; novel CPU architectures and applications; dataflow; innovative architectures and tools for security; next generation computing; insights from negative results.

This book constitutes the refereed proceedings of the 20th International Conference on Embedded Computer Systems: Architectures, Modeling, and Simulation, SAMOS 2020, held in Samos, Greece, in July 2020.*The 16 regular papers presented were carefully reviewed and selected from 35 submissions. In addition, 9 papers from two special sessions were included, which were organized on topics of current interest: innovative architectures for security and European projects on embedded and high performance computing for health applications. * The conference was held virtually due to the COVID-19 pandemic.