CURRENT TOPICS IN MEDICAL MYCOLOGY, VOLUME 4, like the pre- ceding three volumes in the series, is intended to summarize current research advances inmedical mycology. Topics ex- plored in this volume include skin kinetics of azole anti- fungal drugs; killer system interactions; fusarium-caused hyalohyphamycosis; molecular technique for epidemiologic ty- ping of Candida species; and the need for a mycoses-repor- ting system.

Current Topics in Medical Mycology, is intended to summa- rize current research areas in medical mycology for medical mycologists and other scientists who are working in micro- biology and immunology. Topics to be included in each volume will serve as contemporary reviews, summaries of current advancements and future directions, and mecha- nisms to enhance the interdisciplinary use of medically im- portant fungi in understanding pathogenesis, epidemiology, mycotoxins, taxonomy, and other areas where basic, ap- plied, and clinical sciences are used. Michael R. McGinnis Marcel Borgers v Contents v Series Preface Contributors ix 1 Animal Models for Dermatomycotic Infections JAN VAN CUTSEM 1 2 Vaccines for the Management of Dermatophyte and Superficial Yeast Infections ESTHER SEGAL 36 3 Tissue-Bound Immunity: A Mechanism of Can- dacidal Activity HISASHI TAKAHASHI, KENICHIRO CHIKAKANE, MAsARU OKUDA, MARIKO HATANO, MANABU HOSHINO, OSAMU KANEKO, and YOKO KAWA 50 4 Rhinosporidiosis MERANI THIANPRASIT and KLEOPHANT THAGERNGPOL 64 Pathogenesis of Candida Vulvovaginitis 5 JACK D. SOBEL 86 6 Control of Extension of the Hyphal Apex NEIL A. R. Gow 109 7 Epidemiology and Ecology of Pityriasis Versicolor JAN FAERGEMANN 153 8 Fungal Cell Wall Synthesis and Assembly JOSE RUIZ-HERRERA, RAFAEL SENTANDREU 168 vii viii Contents 9 Lipids and Lipoidal Mycotoxins of Fungi MICHAEL A. GEALT, ABBAS ABDOLLAHI, and JOSEPH L.