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This volume provides computational methods and reviews various
aspects of computational studies of protein aggregation. Chapters
discuss the relationship between protein misfolding and protein
aggregation, methods of prediction of aggregation propensities of
protein, peptides, protein structure, results of computer
simulations of aggregation, and computational simulations focused
on specific diseases such as Alzheimer's, Parkinson's, and
preeclampsia. Written in the highly successful Methods in Molecular
Biology series format, chapters include introductions to their
respective topics, lists of the necessary materials and reagents,
step-by-step, readily reproducible laboratory protocols, and tips
on troubleshooting and avoiding known pitfalls. Authoritative and
cutting-edge, Computer Simulations of Aggregation of Proteins and
Peptides aims to ensure successful results in the further study of
this vital field.
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