The Rheumatology Handbook is a unique resource for medical students and non-specialist doctors. It represents a collaborative eff=ort between specialists from major teaching hospitals with in the UK and Ireland, with each chapter being edited by a diffeerent consultant reheumatologist with the relevant subspecialty interest. Writtenh clearly and concisely and will illustrated, the book provides readers with the basic scientific information that they require to understand current concepts about the pathogenesis of rehumatological diseases, and draws on recent reserach studies to give up-to-date information about investigation and treatment. It covers the full range of rheumatological conditions, from local degenerative problems to systemic immune-mediated disease. It includes a useful section on soft-tissue disorders and a practical guide to prerfoming soft-tissue and joint injections: at the other end of the clinical spectrum, the rationale for and efficacy of novel treatments targeted at individual components of the immune response are well explained.