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This Guide assesses the key clinimetric attributes in the
assessment of Parkinson's Disease (PD), with the intention to offer
rapid and pragmatic information on the most relevant scales used in
PD. Parkinson's disease affects approximately 4 million people
globally and is most commonly seen in people over the age of 50.
The disease is a progressive disorder of the nervous system, and
presents a number of movement and cognitive symptoms, thereby
greatly affecting a patients quality of life. The use of scales for
assessment in neurological disorders such as PD arises from the
need to quantify disorders and states (such constructs as
disability, symptoms, quality of life). Assessment scales are often
categorised into two categories: generic (i.e. those scales usable
in any health condition), and specific (i.e. scales developed for
exclusive use in PD). They can have a variety of components:
single-item and multi-item or composite scale; unidimensional and
multidimensional; and as disease-centered and patient-centered
measures. The creation and validation of scales is complex, with
scales undergoing numerous studies to assess criteria such as
acceptability, reliability, and responsiveness. In the process of
validation of a scale the following attributes should be tested to
ascertain whether a scale is an effective instrument of
measurement.
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