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This handbook covers established and advanced techniques for
biomarker analysis, such as guidelines and strategies for assay
validation methods; different mathematical models that are
necessary in contemporary drug discovery and development; and
evaluation of new cytometry methods. Expertly curated by two
practicing professionals in drug development and biotherapeutics,
individual chapters are selected for novel and sound research;
information is chosen based on its relevance to lab applications
and clinical trials, such as the topic of selecting animal models
for their relevancy to humans. The book is multifaceted, discussing
the ethics and issues with biospecimens and providing an in-depth
analysis to the differences between pre-clinical and clinical assay
development. The book is an essential read for general readers who
need an introduction to the history and background of biomarkers,
and it also provides critical analyses of various new validation
methods for practitioners and researchers.
This handbook covers established and advanced techniques for
biomarker analysis, such as guidelines and strategies for assay
validation methods; different mathematical models that are
necessary in contemporary drug discovery and development; and
evaluation of new cytometry methods. Expertly curated by two
practicing professionals in drug development and biotherapeutics,
individual chapters are selected for novel and sound research;
information is chosen based on its relevance to lab applications
and clinical trials, such as the topic of selecting animal models
for their relevancy to humans. The book is multifaceted, discussing
the ethics and issues with biospecimens and providing an in-depth
analysis to the differences between pre-clinical and clinical assay
development. The book is an essential read for general readers who
need an introduction to the history and background of biomarkers,
and it also provides critical analyses of various new validation
methods for practitioners and researchers.
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