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This detailed book explores the concepts and applications of
epigenome editing, as presented by leading scientists in the field.
Beginning with some general and topical reviews, the collection
continues by covering the design of DNA-binding devices,
optimization of the effector domains, readout of epigenome marks,
and approaches for delivery at the cellular and organismal level.
Written for the highly successful Methods in Molecular Biology
series, chapters include introductions to their respective topics,
lists of the necessary materials and reagents, step-by-step,
readily reproducible laboratory protocols, and tips on
troubleshooting and avoiding known pitfalls. Authoritative and
practical, Epigenome Editing: Methods and Protocols will be of
great assistance to people new to the field but also to those
already engaged, as epigenetic editing is still a relatively
unexplored field with many issues to be resolved.
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