This issue covers the full gamut of infectious disease issues encountered in the ICU, including the approach to the febrile patient, management of septic shock, severe community-acquired pneumonia, management of ventilator-associated pneumonia, approach to the immunocompromised host, bloodstream infection, severe soft tissue infections, management of intra-abdominal sepsis, meningitis and brain abscess, treatment of fungal infections, acute infective endocarditis, new antimicrobial agents, antimicrobial stewardship, infection control, and C. difficile infection.

David Frankel directs this comedy drama about a middle-aged couple who seek professional help after running into marital problems. Scripted by Vanessa Taylor, the film tells the story of Arnold and Maeve Soames (Tommy Lee Jones and Meryl Streep), who have hit the rocks after 30 years of marriage. Recognising that they must face the problems in their relationship, they decide to attend an 'intense counseling weekend', where they are taken under the wing of impassioned couples therapist Dr Bernie Feld (Steve Carrell).

Come on a journey with award-winning GP DR AMIR KHAN to discover how families begin and how you became part of your family. Our EXPERTS are famous for their incredible know-how and passion for their subjects, and now they have made it their mission to share that knowledge with you in LITTLE EXPERTS: the inspirational non-fiction series for six- to nine-year-olds. This jaw-dropping non-fiction journey has bold, colourful artwork throughout by Aaron Marin. Little Experts is an unmissable series that will empower and inspire a new generation of experts. Also available in the LITTLE EXPERTS series: Building a Home by GEORGE CLARKE, an architect, writer, lecturer and TV presenter. Superhero Animals by CHRIS PACKHAM CBE, one of the UK’s leading naturalists and an award-winning conservationist, who began his TV career presenting children’s series The Really Wild Show. Why Money Matters by DEBORAH MEADEN, entrepreneur, Dragons’ Den investor and host of the BBC Radio 5 Live’s The Big Green Money Show podcast. Amazing Bodies by DR RONX, award-winning trans non-binary emergency doctor and TV presenter. Marvellous Vehicles by JAMES MAY, a writer and broadcaster who is best known for co-presenting Top Gear and The Grand Tour.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.