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Risk Assessment with Time to Event Models (Paperback): Mark Crane, Michael C. Newman, Peter F. Chapman, John S. Fenlon Risk Assessment with Time to Event Models (Paperback)
Mark Crane, Michael C. Newman, Peter F. Chapman, John S. Fenlon
R1,035 Discovery Miles 10 350 Ships in 12 - 17 working days

How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questions. Risk Assessment with Time to Event Models is the first comprehensive treatment of these methods in the context of ecological risk assessment. Leading experts from industry, academia, and government regulatory agencies explain how these methods can be used to extract more useful information from laboratory data than is present in simple summary statistics like 48-h LC50. The book offers a clear introduction to the field through several approaches, from the introductory to the more mathematical. Risk Assessment with Time to Event Models demonstrates the relevance of time in the analysis and reporting of toxicity data through the use of practical examples from the field of environmental toxicology. It also incorporates helpful analogies from other disciplines that commonly use time to event modeling.

Risk Assessment with Time to Event Models (Hardcover): Mark Crane, Michael C. Newman, Peter F. Chapman, John S. Fenlon Risk Assessment with Time to Event Models (Hardcover)
Mark Crane, Michael C. Newman, Peter F. Chapman, John S. Fenlon
R3,985 R3,405 Discovery Miles 34 050 Save R580 (15%) Ships in 12 - 17 working days

How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questions.

Risk Assessment with Time to Event Models is the first comprehensive treatment of these methods in the context of ecological risk assessment. Leading experts from industry, academia, and government regulatory agencies explain how these methods can be used to extract more useful information from laboratory data than is present in simple summary statistics like 48-h LC50.

The book offers a clear introduction to the field through several approaches, from the introductory to the more mathematical. Risk Assessment with Time to Event Models demonstrates the relevance of time in the analysis and reporting of toxicity data through the use of practical examples from the field of environmental toxicology. It also incorporates helpful analogies from other disciplines that commonly use time to event modeling.

Derivation and Use of Environmental Quality and Human Health Standards for Chemical Substances in Water and Soil (Paperback):... Derivation and Use of Environmental Quality and Human Health Standards for Chemical Substances in Water and Soil (Paperback)
Mark Crane, Peter Matthiessen, Dawn Stretton Maycock, Graham Merrington, Paul Whitehouse
R1,868 Discovery Miles 18 680 Ships in 12 - 17 working days

A balanced, comprehensive overview of Environmental Quality Standards (EQS), Derivation and Use of Environmental Quality and Human Health Standards for Chemical Substances in Water and Soil addresses the selection and prioritization of substances for standard derivation. With integrated content and up-to-date information on assessment of regulations that affect the derivation and use of EQS, it examines the derivation of these standards and their implementation to protect human health and the environment. The book is based on contributions from thirty-five scientists, regulators, and policy makers from eleven countries with individual expertise across disciplines such as risk assessment, environmental, health, economic, and social sciences. These scientists summarize current knowledge on aquatic and terrestrial environmental quality standards, placing these standards in a wider socioeconomic and regulatory context. The book explains how to derive environmental standards that are defensible from a scientific and socioeconomic perspective. Using multidisciplinary techniques applicable to water, sediments, and soils; the text demonstrates how to select the best form and derivation method relative to individual environmental standards. The book presents an in-depth examination of when, where, and how to implement environmental standards based on the social and economic context. It includes detailed coverage of technical approaches that shed light on the derivation and implementation of EQSs. It also identifies future research that will help to underpin the science of environmental and human health standards.

Veterinary Medicines in the Environment (Paperback): Mark Crane, Alistair B. a. Boxall, Katie Barrett Veterinary Medicines in the Environment (Paperback)
Mark Crane, Alistair B. a. Boxall, Katie Barrett
R1,873 Discovery Miles 18 730 Ships in 12 - 17 working days

Examine the Current State of the Science Surface water sampling programs across the globe have shown the presence of many different classes of medicines. The potential risks associated with the release of these medicines into the environment have become an increasingly important issue for environmental regulators. Effects of Veterinary Medicines in the Environment examines the current state of the science in evaluating the potential risks of veterinary medicines to aquatic and terrestrial ecosystems. International Panel Provide Guidance The book brings together more than 30 experts, from eight countries, with expertise in risk assessment, environmental toxicology and chemistry, and environmental policy and regulation. These experts provide guidance, based on standard risk assessment approaches, on how to assess the environmental effects of veterinary medicines. The text discusses pathways to the environment, exposure and effects assessment, and risk assessment and management in terrestrial and aquatic environments. It reviews classes of veterinary medicines and current regulations, identifies the environmental fate of the medicines, and assesses the use of read-across, QSAR, and other modeling approaches. Detailed Coverage of Technical Approaches An examination of the current state of the science, the book provides integrated content in a single source. It provides detailed coverage of technical approaches that helps practitioners better understand the environmental risks of veterinary medicines.

Derivation and Use of Environmental Quality and Human Health Standards for Chemical Substances in Water and Soil (Hardcover):... Derivation and Use of Environmental Quality and Human Health Standards for Chemical Substances in Water and Soil (Hardcover)
Mark Crane, Peter Matthiessen, Dawn Stretton Maycock, Graham Merrington, Paul Whitehouse
R4,547 Discovery Miles 45 470 Ships in 12 - 17 working days

A balanced, comprehensive overview of Environmental Quality Standards (EQS), Derivation and Use of Environmental Quality and Human Health Standards for Chemical Substances in Water and Soil addresses the selection and prioritization of substances for standard derivation. With integrated content and up-to-date information on assessment of regulations that affect the derivation and use of EQS, it examines the derivation of these standards and their implementation to protect human health and the environment.

The book is based on contributions from thirty-five scientists, regulators, and policy makers from eleven countries with individual expertise across disciplines such as risk assessment, environmental, health, economic, and social sciences. These scientists summarize current knowledge on aquatic and terrestrial environmental quality standards, placing these standards in a wider socioeconomic and regulatory context. The book explains how to derive environmental standards that are defensible from a scientific and socioeconomic perspective. Using multidisciplinary techniques applicable to water, sediments, and soils; the text demonstrates how to select the best form and derivation method relative to individual environmental standards.

The book presents an in-depth examination of when, where, and how to implement environmental standards based on the social and economic context. It includes detailed coverage of technical approaches that shed light on the derivation and implementation of EQSs. It also identifies future research that will help to underpin the science of environmental and human health standards.

Trains...Examination of a Life in Addiction (Paperback): Mark Crane Trains...Examination of a Life in Addiction (Paperback)
Mark Crane
R245 Discovery Miles 2 450 Ships in 10 - 15 working days
Love, Actually (Paperback): Mark Crane Love, Actually (Paperback)
Mark Crane
R271 Discovery Miles 2 710 Ships in 10 - 15 working days

There's no such thing as evil. Morality is not spiritual. Love is real. LOVE, ACTUALLY is a book full of new ideas, a book about everything that offers our lives meaning. Mark Crane poses a compelling challenge to readers to rethink basic ideas about cognition, religion, identity, and morality. Using engaging examples and carefully-documented sources, Crane builds a revolutionary case for a reconstruction of our fractured civic relationship with morality.

Veterinary Medicines in the Environment (Hardcover): Mark Crane, Alistair B. a. Boxall, Katie Barrett Veterinary Medicines in the Environment (Hardcover)
Mark Crane, Alistair B. a. Boxall, Katie Barrett
R4,408 Discovery Miles 44 080 Ships in 12 - 17 working days

Examine the Current State of the Science Surface water sampling programs across the globe have shown the presence of many different classes of medicines. The potential risks associated with the release of these medicines into the environment have become an increasingly important issue for environmental regulators. Effects of Veterinary Medicines in the Environment examines the current state of the science in evaluating the potential risks of veterinary medicines to aquatic and terrestrial ecosystems. International Panel Provide Guidance The book brings together more than 30 experts, from eight countries, with expertise in risk assessment, environmental toxicology and chemistry, and environmental policy and regulation. These experts provide guidance, based on standard risk assessment approaches, on how to assess the environmental effects of veterinary medicines. The text discusses pathways to the environment, exposure and effects assessment, and risk assessment and management in terrestrial and aquatic environments. It reviews classes of veterinary medicines and current regulations, identifies the environmental fate of the medicines, and assesses the use of read-across, QSAR, and other modeling approaches. Detailed Coverage of Technical Approaches An examination of the current state of the science, the book provides integrated content in a single source. It provides detailed coverage of technical approaches that helps practitioners better understand the environmental risks of veterinary medicines.

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