Mark Mann identifies the anthropological presuppositions of the holiness tradition and explores the ways that those presuppositions have led to particular assertions regarding the nature of Christian holiness as that doctrine is affirmed by the holiness tradition. He asks to what extent holiness is possible in this life. How is holiness obtained, and to what extent can people gain knowledge of having achieved holiness? Mann uses the resources of the neurosciences, the sociology of knowledge, and psychology to help answer these questions and to provide constructive theological analysis of these questions.