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Showing 1 - 5 of 5 matches in All Departments

Therapeutic Angiogenesis for Vascular Diseases - Molecular Mechanisms and Targeted Clinical Approaches for the Treatment of... Therapeutic Angiogenesis for Vascular Diseases - Molecular Mechanisms and Targeted Clinical Approaches for the Treatment of Angiogenic Disease (Hardcover, 2011 ed.)
Mark S. Levin
R5,518 Discovery Miles 55 180 Ships in 10 - 15 working days

Angiogenesis is the growth of new blood vessels and is a key process which occurs during pathological disease progression. Excessive and damaging angiogenesis occurs in diseases such as cancer, diabetic retinopathies, age-related macular degeneration and atherosclerosis. In other diseases such as stroke and myocardial infarction, insufficient or improper angiogenesis results in tissue loss and ultimately higher morbidity and mortality. In this book we will begin by providing the reader with an overview of the process of angiogenesis including normal embryological development of blood vessels. The following chapters will each focus on a key angiogenic disease incorporating current scientific knowledge concerning the causes of activation of the "angiogenic switch," pathological consequences, current treatment options and future perspectives. Where appropriate, results from pre-clinical trials, novel imaging modalities and nanotechnological approaches will be incorporated into these sections. Finally, since it is now believed that the process of angiogenesis operated via different signalling mechanisms in different vascular beds, we will discuss our current understanding of this phenomenon. The target audience for this book would include researchers in all the basic sciences; post-graduate students at Universities and Institutes; pharmaceutical industries; clinicians working in vascular biology or tissue imaging; pathologists; neurologists; tumour biologists; ophthalmologists and cardiologists.

Handbook of Vascular Biology Techniques (Hardcover): Mark S. Levin, Garry McDowell Handbook of Vascular Biology Techniques (Hardcover)
Mark S. Levin, Garry McDowell
R3,662 Discovery Miles 36 620 Ships in 12 - 17 working days

A wide range of research methods for the study of vascular development, from basic laboratory protocols to advanced technologies used in clinical practice, are covered in this work. A range of methodologies such as molecular imaging platforms and signalling analysis, along with tumour models are collated here. Four sections explore in vitro techniques, in vivo and ex vivo manipulations, imaging and histological analysis and other novel techniques in vascular biology. Readers will discover basic methodologies used for analysis of endothelial cell growth in vitro, including co-culture models of vessel formation. Authors also explore isolation and purification of cells and methods for analysis of data and visualization of localized vasculature with modern imaging platforms. Both animal models and human disease are covered in this work. Each chapter contains helpful sections on trouble shooting, additional notes and links, supporting the reader to carry out protocols. This book will appeal to students, researchers and medical professionals working in all vascular-linked fields such as cardio- and cerebrovascular, cancer and dementia.

Therapeutic Angiogenesis for Vascular Diseases - Molecular Mechanisms and Targeted Clinical Approaches for the Treatment of... Therapeutic Angiogenesis for Vascular Diseases - Molecular Mechanisms and Targeted Clinical Approaches for the Treatment of Angiogenic Disease (Paperback, 2011 ed.)
Mark S. Levin
R5,472 Discovery Miles 54 720 Ships in 10 - 15 working days

Angiogenesis is the growth of new blood vessels and is a key process which occurs during pathological disease progression. Excessive and damaging angiogenesis occurs in diseases such as cancer, diabetic retinopathies, age-related macular degeneration and atherosclerosis. In other diseases such as stroke and myocardial infarction, insufficient or improper angiogenesis results in tissue loss and ultimately higher morbidity and mortality. In this book we will begin by providing the reader with an overview of the process of angiogenesis including normal embryological development of blood vessels. The following chapters will each focus on a key angiogenic disease incorporating current scientific knowledge concerning the causes of activation of the "angiogenic switch", pathological consequences, current treatment options and future perspectives. Where appropriate, results from pre-clinical trials, novel imaging modalities and nanotechnological approaches will be incorporated into these sections. Finally, since it is now believed that the process of angiogenesis operated via different signalling mechanisms in different vascular beds, we will discuss our current understanding of this phenomenon. The target audience for this book would include researchers in all the basic sciences; post-graduate students at Universities and Institutes; pharmaceutical industries; clinicians working in vascular biology or tissue imaging; pathologists; neurologists; tumour biologists; ophthalmologists and cardiologists.

Current Advances in the Medical Application of Nanotechnology (Paperback): Mark S. Levin Current Advances in the Medical Application of Nanotechnology (Paperback)
Mark S. Levin
R2,427 R2,288 Discovery Miles 22 880 Save R139 (6%) Ships in 10 - 15 working days
Canonical Analysis and Factor Comparison (Paperback): Mark S. Levine Canonical Analysis and Factor Comparison (Paperback)
Mark S. Levine
R1,192 Discovery Miles 11 920 Ships in 10 - 15 working days

An advanced study which presumes a knowledge of multiple regression and factor analysis techniques, this paper considers two techniques for comparing entire sets of data, and develops the canonical correlation model as an extension of regression analysis in which there are several dependent variables.

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