Molecular Structure and Biological Activity of Steroids focuses on the indentification of steroid structural features that control particular biological effects. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book. Well-established observations and proposed models are presented, summarizing knowledge of molecular features (e.g., steroid backbone structures, side-chain constitutions, substitution sites, configurations, hydrogen-bonding patterns) that can affect steroid action. The book also provides overviews about recent progress in various frontier fields of steroid research, including such areas as sex steroids, glucocorticoids, aromatase inhibitors, vitamin D metabolites, brassinosteroids, neuromuscular blocking agents, and cardiotonic steroids. Molecular Structure and Biological Activity of Steroids is a "must-have" resource for biochemists, pharmacologists, endocrinologists, biophysicists, and others actively involved in steroid research.

This book explores the potential of geoethics, as designed within the operational criteria of addressing the deeds and values of the human agent as part of the Earth system. It addresses three key questions: i) what should be considered 'geoethics' in an operational sense, ii) what is peripheral to it, and iii) is there a case therefore to establish a denomination, such as geo-humanities or geosophy, to capture a broader scope of thinking about geoscience and its interactions with society and the natural world, for the benefit of the geo-professionals and others. The book begins by framing, contextualising and describing contemporary geoethics, then goes on to cover several examples of geoethical thinking and explores the societal intersections of geosciences in the planetary 'human niche'. The concluding chapter discusses the challenges facing the emerging field of geoethics and how it may evolve in the future. Bringing together a set of experts across multiple interdisciplinary fields this collection will appeal to scholars, researchers, practitioners and students within geosciences and social sciences, political sciences as well as the humanities. It will interest those who are curious about how ethical reflections relate to professional duties, scholarly interests, activities in professional geoscience associations, or responsible citizenship in times of anthropogenic global change.

This book provides an accessible overview of the societal relevance of contemporary geosciences. Engaging various disciplines from humanities and social sciences, the book offers philosophical, cultural, economic, and geoscientific insights into how to contextualise geosciences in the node of Culture and Nature. The authors introduce two perspectives of societal geosciences, both informed by the lens of geoethics. Throughout the text core themes are explored; human agency, the integrity of place, geo-centricity, economy and climate justice, subjective sense-making and spirituality, nationalism, participatory empowerment and leadership in times of anthropogenic global change. The book concludes with a discussion on culture, education, or philosophy of science as aggregating concepts of seemingly disjunct narratives.The diverse intellectual homes of the authors offer a rich resource in terms of how they perceive human agency within the Earth system. Two geoscientific perspectives and fourteen narratives from various cultural, social and political viewpoints contextualise geosciences in the World(s) of the Anthropocene.

This book provides an accessible overview of the societal relevance of contemporary geosciences. Engaging various disciplines from humanities and social sciences, the book offers philosophical, cultural, economic, and geoscientific insights into how to contextualise geosciences in the node of Culture and Nature. The authors introduce two perspectives of societal geosciences, both informed by the lens of geoethics. Throughout the text core themes are explored; human agency, the integrity of place, geo-centricity, economy and climate justice, subjective sense-making and spirituality, nationalism, participatory empowerment and leadership in times of anthropogenic global change. The book concludes with a discussion on culture, education, or philosophy of science as aggregating concepts of seemingly disjunct narratives.The diverse intellectual homes of the authors offer a rich resource in terms of how they perceive human agency within the Earth system. Two geoscientific perspectives and fourteen narratives from various cultural, social and political viewpoints contextualise geosciences in the World(s) of the Anthropocene.