This book presents the creative, arts-based and educative thinking resulting from a "21 day autoethnography challenge" set of self-guided prompts arising from the large-scale collaborative, creative, and global project to explore Massive and Microscopic Sensemaking during COVId-19 Times. It employs a guiding methodological framework of critical autoethnography, narrating the macro and micro experiences of COVID-19 from a first-person, and critically, culturally-informed perspective. The book features chapters creatively responding to the 21-day pandemic experiment through digital autoethnographic artworks, writings, and collaborations. It allowed authors to build embodied sensibilities, practice autoethnographic forms of writing and making, and transform personal experiences through the COVID-19 moment into critical understanding of scale, sense-making, and the relationality of humans, nonhumans, and the planet.