This three-book set is devoted to the prominent bays of the Western North America. The first volume describes San Francisco Bay - a shallow estuary surrounded by a large population center. The forces that built it began with plate tectonics and involved the collision of the Pacific and North American plates and the subduction of the Juan de Fuka plate. Gold mining during the California gold rush sent masses of slit into the Bay. The second volume is devoted to San Diego Bay, which is also a shallow estuary surrounded by a large human population center that influenced the Bay. The third volume describes Puget Sound - a different sort of bay - a complex fjord-estuary system, but also surrounded by several large population centers. The watershed is enormous, covering nearly 43,000 square kilometers with thousands of rivers and streams. Geological forces, volcanos, Ice Ages, and changes in sea levels make the Sound a biologically dynamic and fascinating environment, as well as a productive ecosystem. Key Features Summarizes a complex geological, geographical, and ecological history Reviews how the San Diego Bay has changed and will likely change in the future Examines the different roles of various drivers of Bay ecosystem function Includes the role of humans-both first people and modern populations-on the Bay Explores San Diego Bay as an example of general bay ecological and environmental issues

The Puget Sound is a complex fjord-estuary system in Washington State that is connected to the Pacific Ocean by the Juan de Fuca Strait and surrounded by several large population centers. The watershed is enormous, covering nearly 43,000 square kilometers with thousands of rivers and streams. Geological forces, volcanos, Ice Ages, and changes in sea levels make the Sound a biologically dynamic and fascinating environment, as well as a productive ecosystem. Human activity has also influenced the Sound. Humans built several major cities, such as Seattle and Tacoma, have dramatically affected the Puget Sound. This book describes the natural history and evolution of Puget Sound over the last 100 million years through the present and into the future. Key Features Summarizes a complex geological, geographical, and ecological history Reviews how the Puget Sound has changed and will likely change in the future Examines the different roles of various drivers of the Sound's ecosystem function Includes the role of humans-both first people and modern populations. Explores Puget Sound as an example of general bay ecological and environmental issues

The Puget Sound is a complex fjord-estuary system in Washington State that is connected to the Pacific Ocean by the Juan de Fuca Strait and surrounded by several large population centers. The watershed is enormous, covering nearly 43,000 square kilometers with thousands of rivers and streams. Geological forces, volcanos, Ice Ages, and changes in sea levels make the Sound a biologically dynamic and fascinating environment, as well as a productive ecosystem. Human activity has also influenced the Sound. Humans built several major cities, such as Seattle and Tacoma, have dramatically affected the Puget Sound. This book describes the natural history and evolution of Puget Sound over the last 100 million years through the present and into the future. Key Features Summarizes a complex geological, geographical, and ecological history Reviews how the Puget Sound has changed and will likely change in the future Examines the different roles of various drivers of the Sound's ecosystem function Includes the role of humans-both first people and modern populations. Explores Puget Sound as an example of general bay ecological and environmental issues

Summarizes a complex geological, geographical and ecological history Reviews how the San Diego Bay has changed and will likely change in the future Examines the different roles a various drivers of Bay ecosystem function Includes the role of humans - both first people and modern populations - on the Bay Explores San Diego Bay as an example of general bay ecological and environmental issues

San Francisco Bay is a shallow estuary surrounded by a large population center. The forces that built it began with plate tectonics and involved the collision of the Pacific and North American plates and the subduction of the Juan de Fuka plate. Changes in the climate resulting from the last ice age yielded lower and then higher sea levels. Human activity influenced the Bay. Gold mining during the California gold rush sent masses of slit into the Bay. Humans have also built several major cities and filled significant parts of the Bay. This book describes the natural history and evolution of the SF Bay Area over the last 50 million years through the present and into the future. Key selling features: Summarizes a complex geological, geographical and ecological history Reviews how the San Francisco Bay has changed and will likely change in the future Examines the different roles and various drivers of Bay ecosystem function Includes the role of humans - both first peoples and modern populations - on the Bay Explores San Francisco Bay as an example of general bay ecolgical and environmental issues

San Francisco Bay is a shallow estuary surrounded by a large population center. The forces that built it began with plate tectonics and involved the collision of the Pacific and North American plates and the subduction of the Juan de Fuka plate. Changes in the climate resulting from the last ice age yielded lower and then higher sea levels. Human activity influenced the Bay. Gold mining during the California gold rush sent masses of slit into the Bay. Humans have also built several major cities and filled significant parts of the Bay. This book describes the natural history and evolution of the SF Bay Area over the last 50 million years through the present and into the future. Key selling features: Summarizes a complex geological, geographical and ecological history Reviews how the San Francisco Bay has changed and will likely change in the future Examines the different roles and various drivers of Bay ecosystem function Includes the role of humans - both first peoples and modern populations - on the Bay Explores San Francisco Bay as an example of general bay ecolgical and environmental issues

Summarizes a complex geological, geographical and ecological history Reviews how the San Diego Bay has changed and will likely change in the future Examines the different roles a various drivers of Bay ecosystem function Includes the role of humans - both first people and modern populations - on the Bay Explores San Diego Bay as an example of general bay ecological and environmental issues

Antibodies protect us from a wide range of infectious diseases and cancers and have become an indispensable tool in science-both for conventional immune response research as well as other areas related to protein identification analysis. This second edition of Making and Using Antibodies: A Practical Handbook provides clear guidance on all aspects of how to make and use antibodies for research along with their commercial and industrial applications. Keeping pace with new developments in this area, all chapters in this new edition have been revised, updated, or expanded. Along with discussions of current applications, new material in the book includes chapters on western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present clear descriptions of basic methods for making and using antibodies and supply detailed descriptions of basic laboratory techniques. Each chapter begins with introductory material, allowing for a better understanding of each concept, and practical examples are included to help readers grasp the real-world scenarios in which antibodies play a part. From the eradication of smallpox to combating cancer, antibodies present an attractive solution to a range of biomedical problems. They are relatively easy to make and use, have great flexibility in applications, and are cost effective for most labs. This volume will assist biomedical researchers and students and pave the way for future discovery of new methods for making and using antibodies for a host of applications.