Focal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists.

The United States has had a bitter set of experiences with insurgencies and counterinsurgency operations, but it is by no means alone in having to confront such threats and challenges. Indeed, according to Russian President Dmitry Medvedev, the greatest domestic threat to Russia's security is the ongoing insurgency in the North Caucasus. This insurgency grew out of Russia's wars in Chechnya and has gone on for several years, with no end in sight. Yet, it is hardly known in the West and barely covered even by experts. In view of this insurgency's strategic importance and the fact that the U.S. military can and must learn from other contemporary wars, the Strategic Studies Institute brings attention to the war in this book, to shed more light upon both sides, the Islamist (and nationalist) rebels and Russia, as they wage either an insurgency or counterinsurgency campaign.