This book constitutes the refereed joint proceedings of the First International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2018, the First International Workshop on Deep Learning Fails, DLF 2018, and the First International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2018, held in conjunction with the 21st International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2018, in Granada, Spain, in September 2018. The 4 full MLCN papers, the 6 full DLF papers, and the 6 full iMIMIC papers included in this volume were carefully reviewed and selected. The MLCN contributions develop state-of-the-art machine learning methods such as spatio-temporal Gaussian process analysis, stochastic variational inference, and deep learning for applications in Alzheimer's disease diagnosis and multi-site neuroimaging data analysis; the DLF papers evaluate the strengths and weaknesses of DL and identify the main challenges in the current state of the art and future directions; the iMIMIC papers cover a large range of topics in the field of interpretability of machine learning in the context of medical image analysis.

This book constitutes the refereed joint proceedings of the 5th International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2022, held in September 2022, in conjunction with the 25th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2022. The 10 full papers presented at iMIMIC 2022 were carefully reviewed and selected from 24 submissions each. The iMIMIC papers focus on introducing the challenges and opportunities related to the topic of interpretability of machine learning systems in the context of medical imaging and computer assisted intervention.

This book constitutes the refereed joint proceedings of the 4th International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2020, and the First International Workshop on Topological Data Analysis and Its Applications for Medical Data, TDA4MedicalData 2021, held on September 27, 2021, in conjunction with the 24th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2021.The 7 full papers presented at iMIMIC 2021 and 5 full papers held at TDA4MedicalData 2021 were carefully reviewed and selected from 12 submissions each. The iMIMIC papers focus on introducing the challenges and opportunities related to the topic of interpretability of machine learning systems in the context of medical imaging and computer assisted intervention. TDA4MedicalData is focusing on using TDA techniques to enhance the performance, generalizability, efficiency, and explainability of the current methods applied to medical data.

This book constitutes the refereed joint proceedings of the Second International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2019, and the 9th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2019, held in conjunction with the 22nd International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2019, in Shenzhen, China, in October 2019. The 7 full papers presented at iMIMIC 2019 and the 3 full papers presented at ML-CDS 2019 were carefully reviewed and selected from 10 submissions to iMIMIC and numerous submissions to ML-CDS. The iMIMIC papers focus on introducing the challenges and opportunities related to the topic of interpretability of machine learning systems in the context of medical imaging and computer assisted intervention. The ML-CDS papers discuss machine learning on multimodal data sets for clinical decision support and treatment planning.

This two-volume set LNCS 11383 and 11384 constitutes revised selected papers from the 4th International MICCAI Brainlesion Workshop, BrainLes 2018, as well as the International Multimodal Brain Tumor Segmentation, BraTS, Ischemic Stroke Lesion Segmentation, ISLES, MR Brain Image Segmentation, MRBrainS18, Computational Precision Medicine, CPM, and Stroke Workshop on Imaging and Treatment Challenges, SWITCH, which were held jointly at the Medical Image Computing for Computer Assisted Intervention Conference, MICCAI, in Granada, Spain, in September 2018. The 92 papers presented in this volume were carefully reviewed and selected from 95 submissions. They were organized in topical sections named: brain lesion image analysis; brain tumor image segmentation; ischemic stroke lesion image segmentation; grand challenge on MR brain segmentation; computational precision medicine; stroke workshop on imaging and treatment challenges.

This book constitutes revised selected papers from the Third International MICCAI Brainlesion Workshop, BrainLes 2017, as well as the International Multimodal Brain Tumor Segmentation, BraTS, and White Matter Hyperintensities, WMH, segmentation challenges, which were held jointly at the Medical Image computing for Computer Assisted Intervention Conference, MICCAI, in Quebec City, Canada, in September 2017. The 40 papers presented in this volume were carefully reviewed and selected from 46 submissions. They were organized in topical sections named: brain lesion image analysis; brain tumor image segmentation; and ischemic stroke lesion image segmentation.

This book constitutes the thoroughly refereed post-workshop proceedings of the International Workshop on Brain Lesion, as well as the challenges on Brain Tumor Segmentation (BRATS), Ischemic Stroke Lesion Image Segmentation (ISLES), and the Mild Traumatic Brain Injury Outcome Prediction (mTOP), held in Athens, October 17, 2016, in conjunction with the International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2016. The 26 papers presented in this volume were carefully reviewed. They present the latest advances in segmentation, disease prognosis and other applications to the clinical context.

This book constitutes the refereed joint proceedings of the International Workshop on Computational Methods for Molecular Imaging, CMMI 2017, the International Workshop on Reconstruction and Analysis of Moving Body Organs, RAMBO 2017, and the International Stroke Workshop: Imaging and Treatment Challenges, SWITCH 2017, held in conjunction with the 20th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2017, in Quebec City, QC, Canada, in September 2017. The 5 full papers presented at FIFI 2017, the 9 full papers presented at RAMBO 2017, and the 4 full papers presented at SWITCH 2017 were carefully reviewed and selected. The CMMI papers cover various areas from image synthesis to data analysis and from clinical diagnosis to therapy individualization, using molecular imaging modalities PET, SPECT, PET/CT, SPECT/CT, and PET/MR. The RAMBO papers present research from both academia and industry, They are organized into the categories "registration and tracking" and "image reconstruction and information retrieval" while application areas include cardiac, pulmonal, abdominal, fetal, and renal imaging. The SWITCH papers focus on CT(A)-based quantitative imaging biomarkers for stroke.

This book constitutes the thoroughly refereed post-workshop proceedings of the International Workshop on Brain Lesion (BrainLes), Brain Tumor Segmentation (BRATS) and Ischemic Stroke Lesion Segmentation (ISLES), held in Munich, Germany, on October 5, 2015, in conjunction with the International Conference on Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2015. The 25 papers presented in this volume were carefully reviewed and selected from 28 submissions. They are grouped around the following topics: brain lesion image analysis; brain tumor image segmentation; ischemic stroke lesion image segmentation.

This two-volume set LNCS 11383 and 11384 constitutes revised selected papers from the 4th International MICCAI Brainlesion Workshop, BrainLes 2018, as well as the International Multimodal Brain Tumor Segmentation, BraTS, Ischemic Stroke Lesion Segmentation, ISLES, MR Brain Image Segmentation, MRBrainS18, Computational Precision Medicine, CPM, and Stroke Workshop on Imaging and Treatment Challenges, SWITCH, which were held jointly at the Medical Image Computing for Computer Assisted Intervention Conference, MICCAI, in Granada, Spain, in September 2018. The 92 papers presented in this volume were carefully reviewed and selected from 95 submissions. They were organized in topical sections named: brain lesion image analysis; brain tumor image segmentation; ischemic stroke lesion image segmentation; grand challenge on MR brain segmentation; computational precision medicine; stroke workshop on imaging and treatment challenges.