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The hippocampus has long been considered a critical substrate in
the neurobiology, neuropsychology, and cognitive neuroscience of
memory. Over the past few decades, a number of ground-breaking
theoretical and methodological advances have radically enhanced our
understanding of the structure and function of the hippocampus and
revolutionized the neuroscientific study of memory. Cutting across
disciplines and approaches, these advances offer novel insights
into the molecular and cellular structure and physiology of the
hippocampus, the role of hippocampus in the formation,
(re)consolidation, enhancement, and retrieval of memory across time
and development, and permit investigators to address questions
about how the hippocampus interacts, functionally and anatomically,
with other neural systems in service of memory. In addition, recent
investigations also suggest that the mechanistic properties and
functional processing features of the hippocampus permit broader
contributions to cognition, beyond memory, to the domains of
attention, decision-making, language, social cognition, and a
variety of other capacities that are critical for flexible
cognition and behavior. These advances have profound implications
for the neurobiology and cognitive neuroscience of hippocampus
dependent cognition and for the numerous psychiatric and
neurological diseases and disorders for which hippocampal pathology
is a hallmark such as Alzheimer's disease and schizophrenia. The
goal of this book is to bring together in a single source an
integrated review of these advances providing state of the art
treatment on the structure and function of the hippocampus.
Contributors will examine the hippocampus from a variety of levels
(from cells to systems) using a wide range of methods (from
neurobiological approaches in non-human animals to neuroimaging and
neuropsychological work in humans).
The hippocampus has long been considered a critical substrate in
the neurobiology, neuropsychology, and cognitive neuroscience of
memory. Over the past few decades, a number of ground-breaking
theoretical and methodological advances have radically enhanced our
understanding of the structure and function of the hippocampus and
revolutionized the neuroscientific study of memory. Cutting across
disciplines and approaches, these advances offer novel insights
into the molecular and cellular structure and physiology of the
hippocampus, the role of hippocampus in the formation,
(re)consolidation, enhancement, and retrieval of memory across time
and development, and permit investigators to address questions
about how the hippocampus interacts, functionally and anatomically,
with other neural systems in service of memory. In addition, recent
investigations also suggest that the mechanistic properties and
functional processing features of the hippocampus permit broader
contributions to cognition, beyond memory, to the domains of
attention, decision-making, language, social cognition, and a
variety of other capacities that are critical for flexible
cognition and behavior. These advances have profound implications
for the neurobiology and cognitive neuroscience of hippocampus
dependent cognition and for the numerous psychiatric and
neurological diseases and disorders for which hippocampal pathology
is a hallmark such as Alzheimer’s disease and schizophrenia. The
goal of this book is to bring together in a single source an
integrated review of these advances providing state of the art
treatment on the structure and function of the hippocampus.
Contributors will examine the hippocampus from a variety of levels
(from cells to systems) using a wide range of methods (from
neurobiological approaches in non-human animals to neuroimaging and
neuropsychological work in humans).Â
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