Unlike some other reproductions of classic texts (1) We have not used OCR(Optical Character Recognition), as this leads to bad quality books with introduced typos. (2) In books where there are images such as portraits, maps, sketches etc We have endeavoured to keep the quality of these images, so they represent accurately the original artefact. Although occasionally there may be certain imperfections with these old texts, we feel they deserve to be made available for future generations to enjoy.

This is a true story about a young boy who grew up on a tenant farm in rural Arkansas. Having no hope of obtaining a higher education, he joins the Navy.

This volume brings together a plethora of protocols and experimental methods used by scientists to study calpains, their inhibitors, and their substrates. It also explores bioinformatic approaches to calpain substrate identification. The chapters in this book are divided into five parts and cover topics such as production and purification of calpains; determination of calpain localization, expression, and activity; identification of calpain-activated protein function; interrogation of calpastatin; and manipulation of calpain expression. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Calpain: Methods and Protocols is a valuable resource for researchers and scientists who want to learn more about this developing field, and get inspired to make new discoveries that will aid in diagnosing and treating calpain-related diseases.

Neil Messer brings together a range of theoretical and practical questions raised by current research on the human brain: questions about both the 'ethics of neuroscience' and the 'neuroscience of ethics'. While some of these are familiar to theologians, others have been more or less ignored hitherto, and the field of neuroethics as a whole has received little theological attention. Drawing on both theological ethics and the science-and-theology field, Messer discusses cognitive-scientific and neuroscientific studies of religion, arguing that they do not give grounds to dismiss theological perspectives on the human self. He examines a representative range of topics across the whole field of neuroethics, including consciousness, the self and the value of human life; the neuroscience of morality; determinism, freewill and moral responsibility; and the ethics of cognitive enhancement.

What kind of authority does Scripture have? How is Scripture's authority to be negotiated in relation to other sources of authority? And what are the implications of confessing the Bible to be authoritative? The Bible: Culture, Community and Society seeks to answer these questions, covering three core themes. First, reading the Bible in the context of modernity - the challenges the intellectual history of modernity has posed to the Bible's authority and how historical work can co-exist with a commitment to the Bible as the Word of God. Secondly, the Bible as a text that forms the church community - how the Bible as an authoritative text shapes a culture. Thirdly, reading the Bible as a public text and the challenges posed by holding to the Bible as the Word of God in a religiously diverse context. The highly distinguished contributors include Ben Quash, David Ferguson, Angus Paddison and Zoe Bennett.

This unique and much needed textbook will meet the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker, et al. to help train new drug researchers.
The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, Pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process.
*Uses individual drugs to explain molecular actions
*Full color art program explains molecular and chemical concepts graphically
*Logical structure reflecting the current state of pharmacology and translational research, starting with receptors and finishing with target molecules
*Covers such intricacies as drug resistance and cell death
*Consistent format across chapters and pedagogical strategies make this textbook a superior learning tool

In this controversial and groundbreaking new history, Timothy Messer-Kruse rewrites the standard narrative of the most iconic event in American labor history: the Haymarket Bombing and Trial of 1886. Using thousands of pages of previously unexamined materials, Messer-Kruse demonstrates that, contrary to longstanding historical opinion, the trial was not the "travesty of justice" it has commonly been depicted as. Prosecutors in the trial successfully brought to light a daunting amount of evidence revealing the inner workings of an anarchist conspiracy to spark insurrection by attacking police, and connected their plans to the bomber through a solid chain of evidence. Rather than being an example of "judicial murder," the Haymarket trial was a tragic case of judicial suicide, as the defense chose to use the trial as a grandstand for anarchism rather than deploy a sound legal defense. Though bumblers in the courtroom, the anarchist lawyers proved adept in the court of public opinion and succeeded in influencing the way historians and activists would remember this event for the next 125 years. Exhaustively researched and forcefully argued, this is a vital new contribution to our understanding of labor history and the world of Gilded Age America.

This volume covers the most important contributions to and discussions at the international symposium Migrations: Interdisciplinary Perspectives (1-3, July, University of Vienna), organised by Renee Schroeder and Ruth Wodak which was dedicated to the multiple interdisciplinary dimensions of migrations, both from the viewpoints of the Social Sciences and Humanities as well as from the manifold perspectives of the Natural Sciences. The book is organized along the following dimensions:

Urban Development and Migration

Peer Relations in Immigrant Adolescents: Methodological Challenges and Key Findings

Migration, Identity, and Belonging

Migration in/and Ego Documents

Debating Migration

Fundamentals of Diffusion and Spread in the Natural Sciences and beyond

Media Representations of Migrants and Migration

Migration and the Genes

The book indentifies and assesses the importance of a range of influences on child language acquisition and development, paying particular attention to situational influences. Key issues are highlighted and recent research is presented. There are five sections: the deployment of speech during early development; linguistic interaction and family background - encoding the situation; multidimentional aspects of language development; and constraints on language development. There are twelve chapters on these themes.

Sports are an integral part of American society. Millions of dollars are spent every year on professional, collegiate, and youth athletics, and participation in and viewing of these sports both alter and reflect how one perceives the world. Beamon and Messer deftly explore sports as a social construction, and more significantly, the large role race and ethnicity play in sports and consequently sports' influence on modern race relations. This text is ideal for courses on Sport and Society as well as Race and Ethnicity.

This book examines the lives and tenures of all the consorts of the Tudor and Stuart monarchs of England between 1485 and 1714, as well as the wives of the two Lords Protector during the Commonwealth. The figures in Tudor and Stuart Consorts are both incredibly familiar-especially the six wives of Henry VIII-and exceedingly unfamiliar, such as George of Denmark, the husband of Queen Anne. These innovative and authoritative biographies recognise the important role consorts played in a period before constitutional monarchy: in addition to correcting popular assumptions that are based on limited historical evidence, the chapters provide a fuller picture of the role of consort that goes beyond discussions of exceptionalism and subversion. This volume and its companions reveal the changing nature of English consortship from the Norman Conquest to today.

Angela Poe has been sixteen for four hundred years, and has lived all of her life throughout Europe. To escape the Underworld, she settles in a small town in Tennessee, where she befriends two boys...Now evil threatens their lives, when the day, the becomes night.

This story told in colloquial language of the time is a must read for those who love great family stories about the South. The central character is a young boy and his family on a rented cotton farm in rural Arkansas just before, during and after WWII.

The memorial given Ol' Gray, the horse that was much loved by his father; Ol' Pal the dog of his boyhood; his meeting of Uncle Tom the boot legger; the fear and horror of Polio and many others will surely enthrall you.

The sacrifices of his mother "The General" will touch your heart. We may view religion of that time as quaint in our modern era. But you will marvel at her faith.

The stories are in short essay form and cover periods from the time of the Civil War, as told by his 92-year-old Uncle Floyd, through his fourteenth year.

The influence of his grandparents, parents and siblings are related in a manner that you will come away feeling you know them. You will thrill at their successes and feel pain with their failures.

This book examines the lives and tenures of the consorts of the Plantagenet dynasty during the later Middle Ages, encompassing two major conflicts-the Hundred Years' War and the Wars of the Roses. The figures in this volume include well-known consorts such as the "She Wolves" Isabella of France and Margaret of Anjou, as well as queens who are often overlooked, such as Philippa of Hainault and Joan of Navarre. These innovative and authoritative biographies bring a fresh approach to the consorts of this period-challenging negative perceptions created by complex political circumstances and the narrow expectations of later writers, and demonstrating the breadth of possibilities in later medieval queenship. Their conclusions shed fresh light on both the politics of the day and the wider position of women in this age. This volume and its companions reveal the changing nature of English consortship from the Norman Conquest to today.

In the 1980s, many Americans began to believe that racial problems and institutional discrimination were a thing of the past, but the race issue turned out to be as divisive and powerful as it had ever been. Major events related to race included the Reagan/Carter presidential race, Jesse Jackson's 1984 presidential campaign, the Tawana Brawley case, and President George H. W. Bush's manipulation in his 1998 presidential campaign of convict Willie Horton. The 1990s saw the Immigration Act of 1990 allowing more Asians into the United States, the Anita Hill testimony against the first black U.S. Supreme Court Justice, the Rodney King beating in Los Angeles, and the Million Man March. This volume is THE content-rich source in a desirable decade-by-decade organization to help students and general readers understand the crucial race relations of the recent past. Race Relations in the United States, 1980-2000 provides comprehensive reference coverage of the key events, influential voices, race relations by group, legislation, media influences, cultural output, and theories of inter-group interactions. The volume covers two decades with a standard format coverage per decade, including Timeline, Overview, Key Events, Voices of the Decade, Race Relations by Group, Law and Government, Media and Mass Communications, Cultural Scene, Influential Theories and Views of Race Relations, Resource Guide. This format allows comparison of topics through the decades. The bulk of the coverage is topical essays, written in a clear, encyclopedic style. Historical photos, a selected bibliography, and index complement the text.

This book examines the Tulsa Race Massacre of 1921, perhaps the most lethal and financially devastating instance of collective violence in early twentieth-century America. The Greenwood district, a comparably prosperous black community spanning thirty-five city blocks, was set afire and destroyed by white rioters. This work analyzes the massacre from a sociological perspective, extending an integrative approach to studying its causes, the organizational responses that followed, and the complicated legacy that remains.