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Compaction of powder constituents-both active ingredient and
excipients-is examined to ensure consistent and reproducible
disintegration and dispersion profiles. Revised to reflect modern
pharmaceutical compacting techniques, this second edition of
Pharmaceutical Powder Compaction Technology guides pharmaceutical
engineers, formulation scientists, and product development and
quality assurance personnel through the compaction formulation
process and application. This unique reference covers: The physical
structure of pharmaceutical compacts Bonding phenomena that occur
during powder compaction Compression mechanisms of pharmaceutical
particles Theories and basic principles of powder compaction New
topics include: Compaction data analysis techniques The migration
of powder constituents into commercial manufacture Instrumentation
for compaction Compaction functionality testing, which is likely to
become a USP requirement Design space for compaction Metrics
required for scalability in tablet compression Interactive
compaction and preformulation database for commonly used excipients
Compaction of powder constituents-both active ingredient and
excipients-is examined to ensure consistent and reproducible
disintegration and dispersion profiles. Revised to reflect modern
pharmaceutical compacting techniques, this second edition of
Pharmaceutical Powder Compaction Technology guides pharmaceutical
engineers, formulation scientists, and product development and
quality assurance personnel through the compaction formulation
process and application. This unique reference covers: The physical
structure of pharmaceutical compacts Bonding phenomena that occur
during powder compaction Compression mechanisms of pharmaceutical
particles Theories and basic principles of powder compaction New
topics include: Compaction data analysis techniques The migration
of powder constituents into commercial manufacture Instrumentation
for compaction Compaction functionality testing, which is likely to
become a USP requirement Design space for compaction Metrics
required for scalability in tablet compression Interactive
compaction and preformulation database for commonly used excipients
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