Ana's Story: A Journey of Hope is a work of narrative nonfiction based on Jenna's experiences while interning for UNICEF and documenting lives of children and teens she encountered through her work. The book focuses on Ana, a teenage single mother who is bravely living with, rather than dying from, HIV. Ana's determination has allowed her to overcome abuse and abandonment and fight for an education and a better future for her child. Inspired by the framework of one girl's life, it is also the story of many children around the world who are marginalized and excluded from basic care, support, and education. Jenna Bush sends a message of hope, inclusion and survival, and calls for youth involvement in helping other young people triumph over adversity.
The book features approximately 45 photographs taken by Mia Baxter, Jenna's friend and fellow UNICEF intern, as well as detailed backmatter including A Letter from Jenna Bush; You Can Make A Difference; Protect Yourself, Protect Others; What's the Real Deal? Ten Myths About HIV/AIDS; Do You Know the Whole Story? Ten Myths About Abuse; and Discussion Questions.