There has been considerable increase in the knowledge concern ing tear secretion, the ocular surface, and pathophysiologic con ditions leading to the dry eye. Much of this new knowledge is not widely appreciated. Although there have been proceedings of symposia published, there is no currently available book of suf ficient scope, yet reasonable length, which ties together aspects of this newly acquired knowledge. This textbook is designed to give the ophthalmic practitioner a comprehensive, yet concise, guide line concerning the diagnosis and treatment of the dry eye. We have been able to bring together leading researchers to accom plish the same. We wish to express our special thanks to the company Dr. Mann Pharma of Berlin without whose generous sponsorship we could not have completed our task. The sponsor ship, in bringing together the authors in planning, preparation, and realization of this text, is gratefully acknowledged. Washington/Ulm, March 1992 M. A. Lemp R. Marquardt Contents Introduction 1 Chapter 1 History of the Dry Eye J. Murube . . . . . 3 1 lntroduction 3 2 The Concept of the Dry Eye 5 3 The History of the Causes of the Dry Eye 6 4 The History of the Diagnosis of the Dry Eye 11 5 The History of the Treatment of the Dry Eye 15 6 The Social Response to the Dry Eye 19 References . . . . . . . . . . . . . . . . 19 Chapter 2 Functional Morphology of the Conjunctiva J. W. Rohen and E. Lutjen-Drecoll. With 20 Figures and 3 Tables . . . . . . . . . 35 1 Conjunctiva . . . . . . . .

Ocular Surface Disorders draws together current knowledge of the epidemiology, clinical expression, pathophysiology and available medical and surgical therapies to provide a comprehensive text on the diseases of the ocular surface. This highly illustrated text offers guidance on identifying patients most at risk of developing ocular surface disease, assessing their severity, and developing an effective treatment plan. The book opens by covering the basic anatomy and concepts behind disease of the ocular surface, before going to cover individual diseases, techniques and therapies in detail. An authoritative, international team of contributors provides expert insight and guidance. * Provides a definitive 'go-to' reference for ocular surface specialists, ophthalmologists, optometrists and trainees * Contains both medical and surgical management techniques * Dedicated chapters on specific diseases and treatments

Das "trockene Auge" des Patienten fordert den Augenarzt in den letzten Jahren immer haufiger heraus, auch deshalb, weil das Krankheitsbild zu schwerwiegenden Komplikationen am betroffenen Auge fuhren kann. In diesem Buch wird erstmals eine umfassende Gesamtdarstellung uber diesen Themenbereich gegeben. Dabei wird auf die Ursachen, die Diagnostik und die Therapie sowie die Physiologie und Pathophysiologie der menschlichen Tranenflussigkeit eingegangen. Damit soll die Unsicherheit, die vielfach herrscht, uberwunden werden. Auf eine verstandliche, praxisorientierte Darstellung wurde besonderer Wert gelegt. Dem behandelnden Arzt dient es als Wegweiser fur das adaquate diagnostische und therapeutische Vorgehen bei diesem Krankheitsbild.