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This book provides an introduction to qualitative and quantitative
aspects of human physiology. It examines biological and
physiological processes and phenomena, including a selection of
mathematical models, showing how physiological problems can be
mathematically formulated and studied. It also illustrates how a
wide range of engineering and physics topics, such as electronics,
fluid dynamics, solid mechanics and control theory can be used to
describe and understand physiological processes and systems.
Throughout the text, there are introductions to measuring and
quantifying physiological processes using both signaling and
imaging technologies. This new edition includes updated material on
pathophysiology, metabolism and the TCA cycle, as well as more
advanced worked examples. This book describes the basic structure
and models of cellular systems, the structure and function of the
cardiovascular system, and the electrical and mechanical activity
of the heart, and provides an overview of the structure and
function of the respiratory and nervous systems. It also includes
an introduction to the basic concepts and applications of reaction
kinetics, pharmacokinetic modelling and tracer kinetics. It appeals
to final year biomedical engineering undergraduates and graduates
alike, as well as to practising engineers new to the fields of
bioengineering or medical physics.
This introduction to medical imaging introduces all of the major
medical imaging techniques in wide use in both medical practice and
medical research, including Computed Tomography, Ultrasound,
Positron Emission Tomography, Single Photon Emission Tomography and
Magnetic Resonance Imaging. Principles of Medical Imaging for
Engineers introduces fundamental concepts related to why we image
and what we are seeking to achieve to get good images, such as the
meaning of 'contrast' in the context of medical imaging. This
introductory text separates the principles by which 'signals' are
generated and the subsequent 'reconstruction' processes, to help
illustrate that these are separate concepts and also highlight
areas in which apparently different medical imaging methods share
common theoretical principles. Exercises are provided in every
chapter, so the student reader can test their knowledge and check
against worked solutions and examples. The text considers firstly
the underlying physical principles by which information about
tissues within the body can be extracted in the form of signals,
considering the major principles used: transmission, reflection,
emission and resonance. Then, it goes on to explain how these
signals can be converted into images, i.e., full 3D volumes, where
appropriate showing how common methods of 'reconstruction' are
shared by some imaging methods despite relying on different physics
to generate the 'signals'. Finally, it examines how medical imaging
can be used to generate more than just pictures, but genuine
quantitative measurements, and increasingly measurements of
physiological processes, at every point within the 3D volume by
methods such as the use of tracers and advanced dynamic
acquisitions. Principles of Medical Imaging for Engineers will be
of use to engineering and physical science students and graduate
students with an interest in biomedical engineering, and to their
lecturers.
This book provides an introduction to qualitative and quantitative
aspects of human physiology. It examines biological and
physiological processes and phenomena, including a selection of
mathematical models, showing how physiological problems can be
mathematically formulated and studied. It also illustrates how a
wide range of engineering and physics topics, such as electronics,
fluid dynamics, solid mechanics and control theory can be used to
describe and understand physiological processes and systems.
Throughout the text, there are introductions to measuring and
quantifying physiological processes using both signaling and
imaging technologies. This new edition includes updated material on
pathophysiology, metabolism and the TCA cycle, as well as more
advanced worked examples. This book describes the basic structure
and models of cellular systems, the structure and function of the
cardiovascular system, and the electrical and mechanical activity
of the heart, and provides an overview of the structure and
function of the respiratory and nervous systems. It also includes
an introduction to the basic concepts and applications of reaction
kinetics, pharmacokinetic modelling and tracer kinetics. It appeals
to final year biomedical engineering undergraduates and graduates
alike, as well as to practising engineers new to the fields of
bioengineering or medical physics.
This introduction to medical imaging introduces all of the major
medical imaging techniques in wide use in both medical practice and
medical research, including Computed Tomography, Ultrasound,
Positron Emission Tomography, Single Photon Emission Tomography and
Magnetic Resonance Imaging. Principles of Medical Imaging for
Engineers introduces fundamental concepts related to why we image
and what we are seeking to achieve to get good images, such as the
meaning of 'contrast' in the context of medical imaging. This
introductory text separates the principles by which 'signals' are
generated and the subsequent 'reconstruction' processes, to help
illustrate that these are separate concepts and also highlight
areas in which apparently different medical imaging methods share
common theoretical principles. Exercises are provided in every
chapter, so the student reader can test their knowledge and check
against worked solutions and examples. The text considers firstly
the underlying physical principles by which information about
tissues within the body can be extracted in the form of signals,
considering the major principles used: transmission, reflection,
emission and resonance. Then, it goes on to explain how these
signals can be converted into images, i.e., full 3D volumes, where
appropriate showing how common methods of 'reconstruction' are
shared by some imaging methods despite relying on different physics
to generate the 'signals'. Finally, it examines how medical imaging
can be used to generate more than just pictures, but genuine
quantitative measurements, and increasingly measurements of
physiological processes, at every point within the 3D volume by
methods such as the use of tracers and advanced dynamic
acquisitions. Principles of Medical Imaging for Engineers will be
of use to engineering and physical science students and graduate
students with an interest in biomedical engineering, and to their
lecturers.
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