This book is an international effort to standardize the language, terms, and methods used in ocular toxicology.With over 300 color illustrations this consensus volume provides standards and harmonization for procedures, terminology, and scoring schemes for ocular toxicology. it is essential for industry, pharmaceutical companies, and governmental agencies to help improve the drug development process and to reduce and refine the use of animals in research. Standards for Ocular Toxicology and Inflammation is endorsed by the American College of Veterinary Ophthalmologists.

Fresh approaches to one of the most important poems from medieval Scotland. John Barbour's Bruce, an account of the deeds of Robert I of Scotland (1306-29) and his companions during the so-called wars of independence between England and Scotland, is an important and complicated text. Composed c.1375 during the reign of Robert's grandson, Robert II, the first Stewart king of Scotland (1371-90), the poem represents the earliest surviving complete literary work of any length produced in "Inglis" in late medieval Scotland, andis usually regarded as the starting point for any worthwhile discussion of the language and literature of Early Scots. It has also been used as an essential "historical" source for the career and character of that iconic monarch Robert I. But its narrative defies easy categorisation, and has been variously interpreted as a romance, a verse history, an epic or a chivalric biography. This collection re-assesses the form and purpose of Barbour's great poem. It considers the poem from a variety of perspectives, re-examining the literary, historical, cultural and intellectual contexts in which it was produced, and offering important new insights. Steve Boardman is a Reader in History at the University of Edinburgh. Susan Foran, currently an independent scholar, researches chivalry, war and the idea of nation in late medieval historical writing. Contributors: Steve Boardman, Dauvit Broun, Michael Brown, Susan Foran, Chris Given-Wilson, Theo van Heijnsbergen, Rhiannon Purdie, Bioern Tjallen, Diana B. Tyson, Emily Wingfield.

Essays reconsidering key topics in the history of late medieval Scotland and northern England. The volume celebrates the career of the influential historian of late medieval Scotland and northern England, Dr Alexander (Sandy) Grant. Its contributors engage with the profound shift in thinking about this society in the light of his scholarship, and the development of the "New Orthodoxy", both attending to the legacy of this discourse, and offering new research with which to challenge or amend our understanding of late medieval Scotland and northern England. Dr Grant's famously wide and diverse historical interests are here reflected through three main foci: kingship, lordship and identity. The volume includes significant reassessments of the reputations of two kings, Alexander I of Scotland and Henry V of England; an examination of Richard III's relationship to the lordship of Pontefract; and a study of the development of royal pardon in late medieval Scotland. Further chapters consider the social influence and legal and tenurial rights vested in aristocratic lineages, regional gentry communities, and the leaders of burghal corporations. Finally, the relationship between saints cults, piety and regnal and regional identity in medieval Scotland is scrutinised in chapters on St Margaret and St Ninian.

First extended treatment of the city of St Andrews during the middle ages. St Andrews was of tremendous significance in medieval Scotland. Its importance remains readily apparent in the buildings which cluster the rocky promontory jutting out into the North Sea: the towers and walls of cathedral, castleand university provide reminders of the status and wealth of the city in the Middle Ages. As a centre of earthly and spiritual government, as the place of veneration for Scotland's patron saint and as an ancient seat of learning,St Andrews was the ecclesiastical capital of Scotland. This volume provides the first full study of this special and multi-faceted centre throughout its golden age. The fourteen chapters use St Andrews as a focus for the discussion of multiple aspects of medieval life in Scotland. They examine church, spirituality, urban society and learning in a specific context from the seventh to the sixteenth century, allowing for the consideration of St Andrews alongside other great religious and political centres of medieval Europe.

This book is an international effort to standardize the language, terms, and methods used in ocular toxicology.With over 300 color illustrations this consensus volume provides standards and harmonization for procedures, terminology, and scoring schemes for ocular toxicology. it is essential for industry, pharmaceutical companies, and governmental agencies to help improve the drug development process and to reduce and refine the use of animals in research. Standards for Ocular Toxicology and Inflammation is endorsed by the American College of Veterinary Ophthalmologists.

Exciting fresh perspectives on Edward I as man, king and administrator. The reign of Edward I was one of the most important of medieval England, but the king's activities and achievements have not always received the full attention they deserve. The essays collected here offer fresh insights into Edward's own personality as well as developments in law, governance, war and culture. Edward the man emerges in chapters on his early life, his piety and his family, while the administrator king is discussed in evaluations of his twogreat ministers, his handling of the crucial issue of law and order and the way he managed the realm from abroad through his correspondence. Edward's nobles, both in England and Scotland, naturally appear as vital to understanding the reign, while his rule is set in a British and European context. Overall, the book aims to move the debate on the reign beyond K.B. McFarlane's hugely influential judgement that "Edward I preferred masterfulness to the arts of political management", by highlighting his skills -- and failings -- as a politician and manager.

First extended treatment of the city of St Andrews during the middle ages. St Andrews was of tremendous significance in medieval Scotland. Its importance remains readily apparent in the buildings which cluster the rocky promontory jutting out into the North Sea: the towers and walls of cathedral, castleand university provide reminders of the status and wealth of the city in the Middle Ages. As a centre of earthly and spiritual government, as the place of veneration for Scotland's patron saint and as an ancient seat of learning,St Andrews was the ecclesiastical capital of Scotland. This volume provides the first full study of this special and multi-faceted centre throughout its golden age. The fourteen chapters use St Andrews as a focus for the discussion of multiple aspects of medieval life in Scotland. They examine church, spirituality, urban society and learning in a specific context from the seventh to the sixteenth century, allowing for the consideration of St Andrews alongside other great religious and political centres of medieval Europe. Michael Brown is Professor of Medieval Scottish History, University of St Andrews; Katie Stevenson is Keeper of Scottish History and Archaeology,National Museums Scotland and Senior Lecturer in Late Medieval History, University of St Andrews. Contributors: Michael Brown, Ian Campbell, David Ditchburn, Elizabeth Ewan, Richard Fawcett, Derek Hall, Matthew Hammond,Julian Luxford, Roger Mason, Norman Reid, Bess Rhodes, Catherine Smith, Katie Stevenson, Simon Taylor, Tom Turpie.

The noted Prussian theorist, Carl von Clausewitz wrote about the concentration of forces in space, and the unification of forces in time, as though they were two separate entities. Albert Einstein, however, with the advent of his theories on special and general relativity, linked space and time into one entity - spacetime. Given the complexities of the modern battlespace it is necessary for military commanders and planners to conceive operations using Einstein's concept of spacetime instead of Clausewitz's discreet approach. This is important because the perception of an adaptive enemy's movement is relative to the movement of Marine forces (e.g., Marine Expeditionary Force (MEF)). Therefore, neither combatant will agree on their observations of either space or time. This fact, coupled with the Marine Expeditionary Force's desire to place him in a position of disadvantage, requires the MEF to act faster (in decision-making and execution) so that it might generate more tempo and momentum than its adversary is capable of reacting to. The Marine Corps defines tempo and momentum as controlling the rate of actions and interactions within a campaign to maintain the initiative. "Tempo is relative and not absolute. The focus must be on ensuring that our the MEF's] tempo is superior to an enemy's." This author asserts that to determine tempo and momentum, in relation to one's adversary, the MEF commander must take advantage of information management (IM). This advantage must take place in Einstein's spacetime dimension. This dimension is the theoretical understanding that "space and time...can no longer be thought of as an inert backdrop on which the events of the universe play themselves out; rather, through special and then general relativity, they are intimate players in the events themselves." The ability to think in this dimension should allow the MEF commander to continually assess his position, in motion, relative to a reactive enemy who likewise is in motion. Accordi