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"Much of life can be understood in rational terms if expressed in the language of chemistry. It is an international language, a language without dialects, a language for all time, a language that explains where we came from, what we are, and where the physical world will allow us to go. Chemical Language has great esthetic beauty and links the physical sciences to the b- logical sciences. " from The Two Cultures: Chemistry and Biology by Arthur Kornberg (Nobel Prize in Physiology and Medicine, 1959) Over the past two centuries, chemistry has evolved from a relatively pure disciplinary pursuit to a position of central importance in the physical and life sciences. More generally, it has p- vided the language and methodology that has unified, integrated and, indeed, molecularized the sciences, shaping our understanding of the molecular world and in so doing the direction, development and destiny of scientific research. The "language of chemistry" referred to by my former Stanford colleague is made up of atoms and bonds and their interactions. It is a s- tem of knowledge that allows us to understand structure and events at a molecular level and increasingly to use that understanding to create new knowledge and beneficial change. The words on this page, for example, are detected by the eye in a series of events, now generally understood at the molecular level.
This English edition of a best-selling and award-winning German textbook Reaction Mechanisms: Organic Reactions . Stereochemistry . Modern Synthetic Methods is aimed at those who desire to learn organic chemistry through an approach that is facile to understand and easily committed to memory. Michael Harmata, Norman Rabjohn Distinguished Professor of Organic Chemistry (University of Missouri) surveyed the accuracy of the translation, made certain contributions, and above all adapted its rationalizations to those prevalent in the organic chemistry community in the English-speaking world. Throughout the book fundamental and advanced reaction mechanisms are presented with meticulous precision. The systematic use of red "electron-pushing arrows" allows students to follow each transformation elementary step by elementary step. Mechanisms are not only presented in the traditional contexts of rate laws and substituent effects but, whenever possible, are illustrated using practical, useful and state-of-the-art reactions. The abundance of stereoselective reactions included in the treatise makes the reader familiar with key concepts of stereochemistry. The fundamental topics of the book address the needs of upper-level undergraduate students, while its advanced sections are intended for graduate-level audiences. Accordingly, this book is an essential learning tool for students and a unique addition to the reference desk of practicing organic chemists, who as life-long learners desire to keep abreast of both fundamental and applied aspects of our science. In addition, it will well serve ambitious students in chemistry-related fields such as biochemistry, medicinal chemistry and pharmaceutical chemistry. From the reviews: "Professor Bruckner has further refined his already masterful
synthetic organic chemistry classic; the additions are seamless and
the text retains the magnificent clarity, rigour and precision
which were the hallmark of previous editions. The strength of the
book stems from Professor Bruckner s ability to provide lucid
explanations based on a deep understanding of physical organic
chemistry and to limit discussion to very carefully selected
reaction classes illuminated by exquisitely pertinent examples,
often from the recent literature. The panoply of organic synthesis
is analysed and dissected according to fundamental structural,
orbital, kinetic and thermodynamic principles with an effortless
coherence that yields great insight and never over-simplifies. The
perfect source text for advanced Undergraduate and Masters/PhD
students who want to understand, in depth, the art of synthesis
." "Bruckner s Organic Mechanisms accurately reflects the way
practicing organic chemists think and speak about organic
reactions. The figures are beautifully drawn and show the way
organic chemists graphically depict reactions. It uses a
combination of basic valence bond pictures with more sophisticated
molecular orbital treatments. It handles mechanisms both from the
"electron pushing perspective" and from a kinetic and energetic
view. The book will be very useful to new US graduate students and
will help bring them to the level of sophistication needed to be
serious researchers in organic chemistry." "This is an excellent advanced organic chemistry textbook that
provides a key resource for students and teachers alike."
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