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Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of high current interest written by leading international experts.
Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of hight current interest written by leading international experts.
As the first neurological hospital in the world, founded in 1859,
the National Hospital, Queen Square, and its affiliated Institute
of Neurology remain leading neurological centres providing
exceptional clinical services, teaching and research. Illustrated
by over 100 historical images and much unpublished archival
material, this book provides a comprehensive history of the
National Hospital, the Institute, and their staff. It relates the
ups and downs of the Hospital and Institute in war and peacetime,
their financial struggles, many personality conflicts, efforts to
remain independent and to maintain neurological dominance, academic
and clinical contributions, issues relating to specialisation and
subspecialisation and relations between disciplines, and the
changing roles of the Hospital and Institute. The history is told
from varying perspectives against the backdrop of the evolution of
British clinical neuroscience, the special position of London
medicine, and the influence of world wars, and is set in the
context of modern British social history.
Some of the more interesting elements in the chemistry of life are
less commonly occuring ones such as nickel and molybdenum. This
volume elucidates the chemistry of these elements in important
enzymes and also explores the chemistry of elements that do not
normally occur in biological molecules, but are useful in probing
their structure and function. Topics include: Acquisition and
transport of Ni. Mechanistic action of Ni in a wide variety of
enzymes. Multielectron redox systems involving pterins in proteins.
Chemistry of the pterin and flavin complexes of Mo, Fe, Cu and Ru
ions. Replacement of iron in transferrin by a number of other metal
ions. Use of polypyridyl complexes of ruthenium and other
transition metals as probes of nucleic acid structure through
photochemical reactions.
Biological inorganic chemistry is a field of research at the
interface of inorganic and biological chemistry. The rapidly
developing insights into the role of metals in biological systems
has far-reaching implications not only for biological science but
also for related disciplines, ranging from molecular medicine to
the environment. In each volume the reader, whether engaged in
chemistry, biochemistry, biology or molecular medicine, receives a
comprehensive summary and critical overview of a topic of hight
current interest written by leading international experts.
Biological inorganic chemistry is a field of research at the
interface of inorganic and biological chemistry. The rapidly
developing insights into the role of metals in biological systems
has far-reaching implications not only for biological science but
also for related disciplines, ranging from molecular medicine to
the environment. In each volume the reader, whether engaged in
chemistry, biochemistry, biology or molecular medicine, receives a
comprehensive summary and critical overview of a topic of high
current interest written by leading international experts.
As the first neurological hospital in the world, founded in 1859,
the National Hospital, Queen Square, and its affiliated Institute
of Neurology remain leading neurological centres providing
exceptional clinical services, teaching and research. Illustrated
by over 100 historical images and much unpublished archival
material, this book provides a comprehensive history of the
National Hospital, the Institute, and their staff. It relates the
ups and downs of the Hospital and Institute in war and peacetime,
their financial struggles, many personality conflicts, efforts to
remain independent and to maintain neurological dominance, academic
and clinical contributions, issues relating to specialisation and
subspecialisation and relations between disciplines, and the
changing roles of the Hospital and Institute. The history is told
from varying perspectives against the backdrop of the evolution of
British clinical neuroscience, the special position of London
medicine, and the influence of world wars, and is set in the
context of modern British social history.
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