Applying statistical concepts to biological scenarios, this established textbook continues to be the go-to tool for advanced undergraduates and postgraduates studying biostatistics or experimental design in biology-related areas. Chapters cover linear models, common regression and ANOVA methods, mixed effects models, model selection, and multivariate methods used by biologists, requiring only introductory statistics and basic mathematics. Demystifying statistical concepts with clear, jargon-free explanations, this new edition takes a holistic approach to help students understand the relationship between statistics and experimental design. Each chapter contains further-reading recommendations, and worked examples from today's biological literature. All examples reflect modern settings, methodology and equipment, representing a wide range of biological research areas. These are supported by hands-on online resources including real-world data sets, full R code to help repeat analyses for all worked examples, and additional review questions and exercises for each chapter.

Applying statistical concepts to biological scenarios, this established textbook continues to be the go-to tool for advanced undergraduates and postgraduates studying biostatistics or experimental design in biology-related areas. Chapters cover linear models, common regression and ANOVA methods, mixed effects models, model selection, and multivariate methods used by biologists, requiring only introductory statistics and basic mathematics. Demystifying statistical concepts with clear, jargon-free explanations, this new edition takes a holistic approach to help students understand the relationship between statistics and experimental design. Each chapter contains further-reading recommendations, and worked examples from today's biological literature. All examples reflect modern settings, methodology and equipment, representing a wide range of biological research areas. These are supported by hands-on online resources including real-world data sets, full R code to help repeat analyses for all worked examples, and additional review questions and exercises for each chapter.

Monitoring Ecological Impacts provides the tools needed by professional ecologists, scientists, engineers, planners and managers to design assessment programs that can reliably monitor, detect and allow management of human impacts on the natural environment. The procedures described are well grounded in inferential logic, and the statistical models needed to analyse complex data are given. Step-by-step guidelines and flow diagrams provide the reader with clear and useable protocols, which can be applied in any region of the world and to a wide range of human impacts. In addition, real examples are used to show how the theory can be put into practice. Although the context of this book is flowing water environments, especially rivers and streams, the advice for designing assessment programs can be applied to any ecosystem.

Monitoring Ecological Impacts provides the tools needed to design assessment programs that can reliably monitor, detect, and allow management of human impacts on the natural environment. The procedures described are well-grounded in inferential logic, and the statistical models needed to analyse complex data are given. Step-by-step guidelines and flow diagrams provide clear and useable protocols which can be applied in any region of the world, a wide range of human impacts, and any ecosystem. In addition, real examples are used to show how the theory can be put into practice.

This essential textbook is designed for students or researchers in biology who need to design experiments, sampling programs, or analyze resulting data. The text begins with a revision of estimation and hypothesis testing methods, before advancing to the analysis of linear and generalized linear models. The chapters include such topics as linear and logistic regression, simple and complex ANOVA models, log-linear models, and multivariate techniques. The main analyses are illustrated with many examples from published papers and an extensive reference list to both the statistical and biological literature is also included. The book is supported by a web-site that provides all data sets, questions for each chapter and links to software.

Mitochondrial disorders are a highly diverse group of conditions that can affect almost every major system in the human body, often mimicking common disorders. This clinical variety often results in prolonged and often dangerous, diagnostic delays. This textbook provides a practical framework, to enable rapid identification, investigation, and treatment of mitochondrial disorders across the spectrum of clinical practice. Clinically relevant and comprehensive, this textbook employs a system- and case-based approach for practitioners of all levels. It focuses on major phenotypic features, syndromes and management relevant for clinical practice, within a broad overview of the field. This interactive book supports readers with knowledge distilled from over 20 internationally recognized, mitochondrial experts.