Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of high current interest written by leading international experts.

Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of hight current interest written by leading international experts.

Some of the more interesting elements in the chemistry of life are less commonly occuring ones such as nickel and molybdenum. This volume elucidates the chemistry of these elements in important enzymes and also explores the chemistry of elements that do not normally occur in biological molecules, but are useful in probing their structure and function. Topics include: Acquisition and transport of Ni. Mechanistic action of Ni in a wide variety of enzymes. Multielectron redox systems involving pterins in proteins. Chemistry of the pterin and flavin complexes of Mo, Fe, Cu and Ru ions. Replacement of iron in transferrin by a number of other metal ions. Use of polypyridyl complexes of ruthenium and other transition metals as probes of nucleic acid structure through photochemical reactions.

Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of hight current interest written by leading international experts.

Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of high current interest written by leading international experts.

As the first neurological hospital in the world, founded in 1859, the National Hospital, Queen Square, and its affiliated Institute of Neurology remain leading neurological centres providing exceptional clinical services, teaching and research. Illustrated by over 100 historical images and much unpublished archival material, this book provides a comprehensive history of the National Hospital, the Institute, and their staff. It relates the ups and downs of the Hospital and Institute in war and peacetime, their financial struggles, many personality conflicts, efforts to remain independent and to maintain neurological dominance, academic and clinical contributions, issues relating to specialisation and subspecialisation and relations between disciplines, and the changing roles of the Hospital and Institute. The history is told from varying perspectives against the backdrop of the evolution of British clinical neuroscience, the special position of London medicine, and the influence of world wars, and is set in the context of modern British social history.

As the first neurological hospital in the world, founded in 1859, the National Hospital, Queen Square, and its affiliated Institute of Neurology remain leading neurological centres providing exceptional clinical services, teaching and research. Illustrated by over 100 historical images and much unpublished archival material, this book provides a comprehensive history of the National Hospital, the Institute, and their staff. It relates the ups and downs of the Hospital and Institute in war and peacetime, their financial struggles, many personality conflicts, efforts to remain independent and to maintain neurological dominance, academic and clinical contributions, issues relating to specialisation and subspecialisation and relations between disciplines, and the changing roles of the Hospital and Institute. The history is told from varying perspectives against the backdrop of the evolution of British clinical neuroscience, the special position of London medicine, and the influence of world wars, and is set in the context of modern British social history.