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Examples from various organs and diseases illustrate the potential
benefit obtained when both therapeutic approaches are combined with
delivery strategies. Representing the combined effort of several
leading international research and clinical experts, this book,
Emerging Trends in Cell and Gene Therapy, provides a complete
account on and brings into sharp focus current trends and
state-of-the-art in important areas at the interface of cell- and
gene-based therapies. This book addresses the current fragmented
understanding regarding these two research areas and fills the vast
unmet educational need and interest of both students and
researchers in academia and industry. Main features of the book: *
Biological aspects of stem cell sources, differentiation and
engineering. * Application of microfluidics to study stem cell
dynamics * Potential clinical application of stem cells and gene
therapy to specific human disease. * Utilization of biomaterials
and stem cells in regenerative medicine with particular emphasis on
spinal cord repair, ligament and bone tissue engineering. *
Biomimetic multiscale topography for cell alignment.
Examples from various organs and diseases illustrate the potential
benefit obtained when both therapeutic approaches are combined with
delivery strategies. Representing the combined effort of several
leading international research and clinical experts, this book,
Emerging Trends in Cell and Gene Therapy, provides a complete
account on and brings into sharp focus current trends and
state-of-the-art in important areas at the interface of cell- and
gene-based therapies. This book addresses the current fragmented
understanding regarding these two research areas and fills the vast
unmet educational need and interest of both students and
researchers in academia and industry. Main features of the book: *
Biological aspects of stem cell sources, differentiation and
engineering. * Application of microfluidics to study stem cell
dynamics * Potential clinical application of stem cells and gene
therapy to specific human disease. * Utilization of biomaterials
and stem cells in regenerative medicine with particular emphasis on
spinal cord repair, ligament and bone tissue engineering. *
Biomimetic multiscale topography for cell alignment.
Emerging Phytosynthesized Nanomaterials for Biomedical Applications
provides readers with an increased understanding of the efficacy of
phytochemicals obtained from plant extracts for the synthesis of
nanomaterials, mechanism of formation, and the development of
functional composites, all while still minimizing toxicity to
humans and the environment. The book presents various novel
biomedical applications of phytosynthesized nanomaterials for
cancer, diabetes and cardiovascular treatment, drug delivery,
antimicrobial agents, orthopedics, and biosensors, as well as
pharmaceutical product development. This is an important reference
source for biomaterials scientists and plant scientists looking to
increase their understanding of how photosynthesized nanomaterials
can be used in biomedical applications.
Next Generation Nanochitosan: Applications in Animal Husbandry,
Aquaculture and Food Conservation provides comprehensive and
state-of-the-art-information on the application of nanochitosan for
improving products, especially for the evaluation of biological
active molecules, disease therapeutics, transport vehicle for DNA,
targeted drug delivery, gene therapy, development of smart and high
performance of fish, preservation of foods, tissue engineering, and
improving the taste of aquatic and animal feeds as fish growth
promoter. this book will be especially useful for industrial
fisheries who deal with wild capture fishing and aquafarming and
scientists and engineers working on post-capture processing stages.
Details on the application of nanochitosan as an effective delivery
of vaccines, hormones, vitamins, nutrients and antioxidants,
biological active constituents and their wider application for the
protection and management of farm animals and fishes against
disease-causing pathogens are provided.
Bionanotechnology: Emerging Applications of Bionanomaterials
highlights a wide range of industrial applications using
bionanotechnologies, with biomedical applications prominent amongst
these, including drug delivery, tissue engineering, wound healing,
medical implants, medical diagnostics and therapy. Other key areas
include energy harvesting and storage, water/waste treatment,
papermaking, textiles, construction industry, automotive,
aerospace. This book is a valuable resource for all those seeking
to gain a fundamental understanding of how bionanomaterials are
used in a variety of industry sectors. Bionanomaterials are
molecular materials composed partially or completely of biological
molecules - such as proteins, enzymes, viruses, DNA and biopolymers
- as well as metal, metal oxides, and carbon nanomaterials.
Bionanomaterials have drawn much attention for their use in a wide
range of industrial applications, including scaffolds, dental
implants, drug delivery, dialysis, biobatteries, biofuel cells, air
purification, and water treatment.
Emerging Nanomedicines for Diabetes Mellitus Theranostics provides
readers with information on the development of efficacious
nanomedicines as potential theranostic agents for diabetes. The
book discusses the application of various novel nanomaterials and
nanocomposites for targeted delivery of insulin, glucose sensing,
including nano-tattoos as glucose monitors, biosynthesized
nanoparticles for diabetes treatment, and pre-clinical and clinical
assays to evaluate the efficacy of nanomedicines for diabetes
treatment. This is an important references source for materials
scientists, pharmaceutical scientists and biomedical engineers who
want to increase their understanding of how nanotechnology is being
used to improve diabetes treatment. Diabetes has emerged as one of
the most common diseases associated with lifestyle choices in the
modern world, with significant mortality rates. Conventional
treatment methods mainly involve insulin-based therapies. However,
insulin therapy possesses several limitations such as weight gain
and hypoglycemia. Thus, advanced research in nanomedicine is
targeting the development of new and improved diagnostics and
treatment methods for diabetes.
Bionanomaterials are identified as a perfect replacement, in the
quest for the search of an alternative to toxic conventional
nanomaterials for biomedical applications. Bionanomaterials are the
nanomaterials, that are fabricated via biomolecules or encapsulate
or immobilize a conventional nanomaterial with a biomolecule. The
biomolecules extracted from the microbes, plants, agricultural
wastes, insects, marine organisms and certain animals are used for
the formation of bionanomaterials. These bionanomaterials exhibited
low or negligible toxicity towards humans, other organisms and the
environment with enhanced biocompatibility, bioavailability and
bioreactivity. Thus, the aim of this book is to provide an overview
of various bionanomaterials, their synthesis, characterization and
their application-oriented properties. The book is divided into two
parts - Part 1 discusses about the bionanomaterials of exclusive
natural origin, self-assembled bionanomaterials and their
environmental application and Part 2 focuses on applications of
distinct bionanomaterials in biomedical sciences. The 'Chapter 1 -
Bionanomaterials: Definitions, sources, types, properties, market,
toxicity and regulations' aims to provide an extensive overview of
bionanomaterials, their definitions, sources, types and their
properties. In addition, the toxicity of bionanomaterials and their
regulations implied in recent times were also discussed. 'Chapter 2
- Nature inspired bionanomaterials' highlights different types of
nature-inspired biosynthesized nanomaterials and their green
synthesis methods, as well as some of their emerging applications,
especially in the fields of nanomedicine, cosmetics, drug delivery,
molecular imaging, and catalytic precursors. Further, the chapter
also covers different types of bionanomaterials (e.g., viruses,
protein cages, and phages) and highlights their unique properties
and potential applications. 'Chapter 3 - Culinary spices mediated
biogenesis of nanoparticles for cancer and diabetes treatment'
deals with bionanomaterials synthesized by using extracts of
culinary spices and its vital role in the treatment of distinct
types of cancer and diabetes. In 'Chapter 4 - Environment friendly
superhydrophobic bioactive nanocoatings', the authors have
discussed the basics of exceptional water repellence behaviour and
recent developments in the area of bioactive-SHC for various
applications. In addition, the current and projected requirements
for bioactive-SHC were also addressed. The authors of 'Chapter 5 -
Self-assembly of nanobionics: from theory to application' reviewed,
discussed, addressed and highlighted the recent advancements in
bionics as an interdisciplinary field to understand the bionic
materials and particles, that are mainly fabricated via
self-assembly approach. In part 2, the 'Chapter 6 - Inorganic
bionanomaterials for biomedical applications' provides an overview
of inorganic bionanomaterials, its distinct types, synthesis
procedures, properties and characteristics, which is essential for
desired applications. 'Chapter 7 - Polymer nanomaterials for
biomedical applications' is a comprehensive review of various
polymer nanocomposite types, and further describes the synthesis,
preparation, structure and biomedical application of
nanocomposites. In addition, the recent developments in the field
of polymer nanocomposites for biomedical applications were also
discussed. 'Chapter 8 - Lignin nanoparticles and their biomedical
applications' aims in highlighting the current trends in lignin
nanoparticle depolymerization approach, focusing on microbial
lignin degradation, optimization, and its biomedical applications.
The authors of 'Chapter 9 - Polymer-based nanomaterials for
targeted drug delivery' addressed the use of polymeric
bionanomaterials, including hydrogels, electrospun nanofibrous
scaffolds, nanocellulose, and carbohydrate nanocarriers with
special emphasis to their material properties, fabrication
technologies and applicability in specific targeted anatomical
sites. Moreover, 'Chapter 10 - Cationic nanoparticles for treatment
of neurological diseases' discusses about brain disorders, the role
of nutraceuticals, mechanisms, delivery challenges, as well as
formulation techniques and prospects of cationic nanoparticles in
the therapeutic management of neuronal disorders, i.e., brain as
site of drug target. Besides, 'Chapter 11 - Carbon nanomaterials
for therapeutic applications' has highlighted the cutting-edge
properties, mechanism of action, and advancements of carbon
nanomaterials as drug delivery system in various diseases, such as
cancer and inflammatory disorders. Further, the chapter also sheds
light on the potential challenges, limitations, and future outlook
for improving and growing carbon-based bionanomaterials. The final
chapter 'Chapter 12 - Liposomal bionanomaterials for nucleic acid
delivery' is a brief summary of various nucleic acid-based cationic
liposomes as a potential bionanomaterial and its recent progress in
the application of therapeutic nucleic acid delivery. We hope that
this book will enlighten undergraduates, graduates, and industrial
as well as academic researchers on the synthesis, characterization
and property-oriented applications of certain exclusive
bionanomaterials.
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