Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book: * Biological aspects of stem cell sources, differentiation and engineering. * Application of microfluidics to study stem cell dynamics * Potential clinical application of stem cells and gene therapy to specific human disease. * Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. * Biomimetic multiscale topography for cell alignment.

Next Generation Nanochitosan: Applications in Animal Husbandry, Aquaculture and Food Conservation provides comprehensive and state-of-the-art-information on the application of nanochitosan for improving products, especially for the evaluation of biological active molecules, disease therapeutics, transport vehicle for DNA, targeted drug delivery, gene therapy, development of smart and high performance of fish, preservation of foods, tissue engineering, and improving the taste of aquatic and animal feeds as fish growth promoter. this book will be especially useful for industrial fisheries who deal with wild capture fishing and aquafarming and scientists and engineers working on post-capture processing stages. Details on the application of nanochitosan as an effective delivery of vaccines, hormones, vitamins, nutrients and antioxidants, biological active constituents and their wider application for the protection and management of farm animals and fishes against disease-causing pathogens are provided.

Bionanotechnology: Emerging Applications of Bionanomaterials highlights a wide range of industrial applications using bionanotechnologies, with biomedical applications prominent amongst these, including drug delivery, tissue engineering, wound healing, medical implants, medical diagnostics and therapy. Other key areas include energy harvesting and storage, water/waste treatment, papermaking, textiles, construction industry, automotive, aerospace. This book is a valuable resource for all those seeking to gain a fundamental understanding of how bionanomaterials are used in a variety of industry sectors. Bionanomaterials are molecular materials composed partially or completely of biological molecules - such as proteins, enzymes, viruses, DNA and biopolymers - as well as metal, metal oxides, and carbon nanomaterials. Bionanomaterials have drawn much attention for their use in a wide range of industrial applications, including scaffolds, dental implants, drug delivery, dialysis, biobatteries, biofuel cells, air purification, and water treatment.

Emerging Nanomedicines for Diabetes Mellitus Theranostics provides readers with information on the development of efficacious nanomedicines as potential theranostic agents for diabetes. The book discusses the application of various novel nanomaterials and nanocomposites for targeted delivery of insulin, glucose sensing, including nano-tattoos as glucose monitors, biosynthesized nanoparticles for diabetes treatment, and pre-clinical and clinical assays to evaluate the efficacy of nanomedicines for diabetes treatment. This is an important references source for materials scientists, pharmaceutical scientists and biomedical engineers who want to increase their understanding of how nanotechnology is being used to improve diabetes treatment. Diabetes has emerged as one of the most common diseases associated with lifestyle choices in the modern world, with significant mortality rates. Conventional treatment methods mainly involve insulin-based therapies. However, insulin therapy possesses several limitations such as weight gain and hypoglycemia. Thus, advanced research in nanomedicine is targeting the development of new and improved diagnostics and treatment methods for diabetes.

Bionanomaterials are identified as a perfect replacement, in the quest for the search of an alternative to toxic conventional nanomaterials for biomedical applications. Bionanomaterials are the nanomaterials, that are fabricated via biomolecules or encapsulate or immobilize a conventional nanomaterial with a biomolecule. The biomolecules extracted from the microbes, plants, agricultural wastes, insects, marine organisms and certain animals are used for the formation of bionanomaterials. These bionanomaterials exhibited low or negligible toxicity towards humans, other organisms and the environment with enhanced biocompatibility, bioavailability and bioreactivity. Thus, the aim of this book is to provide an overview of various bionanomaterials, their synthesis, characterization and their application-oriented properties. The book is divided into two parts - Part 1 discusses about the bionanomaterials of exclusive natural origin, self-assembled bionanomaterials and their environmental application and Part 2 focuses on applications of distinct bionanomaterials in biomedical sciences. The 'Chapter 1 - Bionanomaterials: Definitions, sources, types, properties, market, toxicity and regulations' aims to provide an extensive overview of bionanomaterials, their definitions, sources, types and their properties. In addition, the toxicity of bionanomaterials and their regulations implied in recent times were also discussed. 'Chapter 2 - Nature inspired bionanomaterials' highlights different types of nature-inspired biosynthesized nanomaterials and their green synthesis methods, as well as some of their emerging applications, especially in the fields of nanomedicine, cosmetics, drug delivery, molecular imaging, and catalytic precursors. Further, the chapter also covers different types of bionanomaterials (e.g., viruses, protein cages, and phages) and highlights their unique properties and potential applications. 'Chapter 3 - Culinary spices mediated biogenesis of nanoparticles for cancer and diabetes treatment' deals with bionanomaterials synthesized by using extracts of culinary spices and its vital role in the treatment of distinct types of cancer and diabetes. In 'Chapter 4 - Environment friendly superhydrophobic bioactive nanocoatings', the authors have discussed the basics of exceptional water repellence behaviour and recent developments in the area of bioactive-SHC for various applications. In addition, the current and projected requirements for bioactive-SHC were also addressed. The authors of 'Chapter 5 - Self-assembly of nanobionics: from theory to application' reviewed, discussed, addressed and highlighted the recent advancements in bionics as an interdisciplinary field to understand the bionic materials and particles, that are mainly fabricated via self-assembly approach. In part 2, the 'Chapter 6 - Inorganic bionanomaterials for biomedical applications' provides an overview of inorganic bionanomaterials, its distinct types, synthesis procedures, properties and characteristics, which is essential for desired applications. 'Chapter 7 - Polymer nanomaterials for biomedical applications' is a comprehensive review of various polymer nanocomposite types, and further describes the synthesis, preparation, structure and biomedical application of nanocomposites. In addition, the recent developments in the field of polymer nanocomposites for biomedical applications were also discussed. 'Chapter 8 - Lignin nanoparticles and their biomedical applications' aims in highlighting the current trends in lignin nanoparticle depolymerization approach, focusing on microbial lignin degradation, optimization, and its biomedical applications. The authors of 'Chapter 9 - Polymer-based nanomaterials for targeted drug delivery' addressed the use of polymeric bionanomaterials, including hydrogels, electrospun nanofibrous scaffolds, nanocellulose, and carbohydrate nanocarriers with special emphasis to their material properties, fabrication technologies and applicability in specific targeted anatomical sites. Moreover, 'Chapter 10 - Cationic nanoparticles for treatment of neurological diseases' discusses about brain disorders, the role of nutraceuticals, mechanisms, delivery challenges, as well as formulation techniques and prospects of cationic nanoparticles in the therapeutic management of neuronal disorders, i.e., brain as site of drug target. Besides, 'Chapter 11 - Carbon nanomaterials for therapeutic applications' has highlighted the cutting-edge properties, mechanism of action, and advancements of carbon nanomaterials as drug delivery system in various diseases, such as cancer and inflammatory disorders. Further, the chapter also sheds light on the potential challenges, limitations, and future outlook for improving and growing carbon-based bionanomaterials. The final chapter 'Chapter 12 - Liposomal bionanomaterials for nucleic acid delivery' is a brief summary of various nucleic acid-based cationic liposomes as a potential bionanomaterial and its recent progress in the application of therapeutic nucleic acid delivery. We hope that this book will enlighten undergraduates, graduates, and industrial as well as academic researchers on the synthesis, characterization and property-oriented applications of certain exclusive bionanomaterials.

Examples from various organs and diseases illustrate the potential benefit obtained when both therapeutic approaches are combined with delivery strategies. Representing the combined effort of several leading international research and clinical experts, this book, Emerging Trends in Cell and Gene Therapy, provides a complete account on and brings into sharp focus current trends and state-of-the-art in important areas at the interface of cell- and gene-based therapies. This book addresses the current fragmented understanding regarding these two research areas and fills the vast unmet educational need and interest of both students and researchers in academia and industry. Main features of the book: * Biological aspects of stem cell sources, differentiation and engineering. * Application of microfluidics to study stem cell dynamics * Potential clinical application of stem cells and gene therapy to specific human disease. * Utilization of biomaterials and stem cells in regenerative medicine with particular emphasis on spinal cord repair, ligament and bone tissue engineering. * Biomimetic multiscale topography for cell alignment.

Emerging Phytosynthesized Nanomaterials for Biomedical Applications provides readers with an increased understanding of the efficacy of phytochemicals obtained from plant extracts for the synthesis of nanomaterials, mechanism of formation, and the development of functional composites, all while still minimizing toxicity to humans and the environment. The book presents various novel biomedical applications of phytosynthesized nanomaterials for cancer, diabetes and cardiovascular treatment, drug delivery, antimicrobial agents, orthopedics, and biosensors, as well as pharmaceutical product development. This is an important reference source for biomaterials scientists and plant scientists looking to increase their understanding of how photosynthesized nanomaterials can be used in biomedical applications.