Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

The Eliot Tracts collects for the first time a series of 11 documents published in London between 1643 and 1671 that describe missionary work by the British among the Indians in New England. Written by John Eliot, Thomas Shepard, and other intellectual and political leaders among the colonists, these tracts constitute the most detailed and sustained record of missionary activity by the English in the New World in the first century of settlement. They are also one of our richest sources of ethnographic information about the Indians of Southern New England in the 17th century as recorded by the British settlers. In addition to the tracts, the volume contains two letters written by John Eliot that argue for the millennialist significance of the missionary work and so situate the missionaries' project within one of the most important theological debates of the time.

The introduction establishes the historical and theological context in which the tracts were written and published. The text of the tracts and letters is that of the original 17th-century publications, including interlinear English/Algonquian translations. Functional variations in relative font size and spacing have been retained to reproduce the visual organization of the original documents, though simplified and regularized across all the tracts to give the volume a visual conformity and coherence. An index allows readers to trace the record of particular towns and individual proselytes and missionaries across the 30 years covered by the tracts, and to follow the contributions of the different authors as they recount their experiences over that period.

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

This cutting-edge collection of essays showcases the work of some of the most influential theorists of the past thirty years as they grapple with the question of how literature should be treated in contemporary theory. The contributors challenge trends that have recently dominated the field--especially those that emphasize social and political issues over close reading and other analytic methods traditionally associated with literary criticism. Written especially for this collection, these essays argue for the importance of aesthetics, poetics, and aesthetic theory as they present new and stimulating perspectives on the directions which theory and criticism will take in the future.
In addition to providing a selection of distinguished critics writing at their best, this collection is valuable because it represents a variety of fields and perspectives that are not usually found together in the same volume. Michael Clark's introduction provides a concise, cogent history of major developments and trends in literary theory from World War II to the present, making the entire volume essential reading for students and scholars of literature, literary theory, and philosophy.