In Tumor Targeting in Cancer Therapy, Dr. Michel Page and a panel of authoritative experts from the drug industry, clinics, and academia introduce the principles and techniques of tumor targeting and critically survey their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme prodrug immunotherapy, and immunotherapeutics with fusion proteins. There are also reviews of targeting tumors with radioimmunoconjugates, photodynamic therapy, and magnetic drugs, as well as discussions of the internalization of antibodies, bioconjugation and biodistribution, the use of cytotoxic drugs, and the pros and cons of targeting by antibody or ligand.

Essentials of Business Research Methods provides an accessible and comprehensive introduction to research methods and analytical techniques for business students. The authors offer a straightforward, hands-on approach to the vital managerial process of gathering and using data to make relevant and timely business decisions. Covering both qualitative and quantitative analysis, the book explores critical topics, including ethics in business research, privacy matters, data analytics, customer relationship management, how to conduct information-gathering activities more effectively in a rapidly changing business environment, and more. This fifth edition has been fully updated throughout, covering emerging technologies such as machine learning and blockchain technology, as well as expanded coverage of secondary data, using examples from around the world. A realistic continuing case used throughout the book, applied research examples and ethical dilemma mini cases, enable upper-level undergraduate and postgraduate students to see how business research information is used in the real world. This comprehensive textbook is supported by a range of online resources, including an instructor’s manual, PowerPoint slides, and a test bank.

Essentials of Business Research Methods provides an accessible and comprehensive introduction to research methods and analytical techniques for business students. The authors offer a straightforward, hands-on approach to the vital managerial process of gathering and using data to make relevant and timely business decisions. Covering both qualitative and quantitative analysis, the book explores critical topics, including ethics in business research, privacy matters, data analytics, customer relationship management, how to conduct information-gathering activities more effectively in a rapidly changing business environment, and more. This fifth edition has been fully updated throughout, covering emerging technologies such as machine learning and blockchain technology, as well as expanded coverage of secondary data, using examples from around the world. A realistic continuing case used throughout the book, applied research examples and ethical dilemma mini cases, enable upper-level undergraduate and postgraduate students to see how business research information is used in the real world. This comprehensive textbook is supported by a range of online resources, including an instructor’s manual, PowerPoint slides, and a test bank.

No society can escape population ageing. This demographic phenomenon has profound social consequences on the lifestyles of individuals and societies. In the light of the accelerated ageing of the Mediterranean area, the analyses which inform this work aim to understand how the age-related policies of Nation-States are partly responsible for the behaviours of the generations. They also highlight how the lifestyle changes are the result of trends which are common to these societies. The Mediterranean area constructed here by the researchers offers an in-depth reflection on the national cases presented, in terms of their specificities or societal singularities, as well as of their dynamics of convergence. Drawing on empirical research in sociology, demography, geography and economics, exploiting the most recent data available and setting the present in historical perspective, Ageing, Lifestyles and Economic Crises studies Mediterranean societies in relation to three major challenges which they now confront. These are: population ageing and its implications in terms of intergenerational family support relationships; increasingly insecure adult professional trajectories and their consequences for the evolution of social gender roles, in an economic context commonly referred to as a 'crisis'; and lastly the role of Nation-States' public policies in the social reproduction of these gender inequalities. These three issues are the keystone to understanding the ongoing transformations in the lifestyles and life cycles of Mediterranean societies. This volume marshals a wealth of recent data that will be useful not only to many academics and scientists but also to local and national policy-makers.

What exactly is the Human Mind? Unique in this entire world, yes, but how exactly does it work, what exactly is it made of? Where exactly is it? And the question the author poses is-is your thinking mind actually what the Bible refers to as your spiritual soul? And if it really is a spiritual soul, can it really survive mortal death? What force powers it? Just flesh and blood, or is there some other invisible divine force behind its incredible powers? The author confesses to having been born into this life complete with memories of several previous lives. It was after these previous lives that he also remembers being born, literally remembering being squeezed out of his mother's womb! And if that is not amazing enough, he also truly believes that he can remember being conceived in his mother's womb. A dramatic out-of-body experience has given the author confirmation that your id, your inner being and your purest spiritual form, can and will survive outside the-body, quite independently, without any body mass...The author was once a sailor on a Tall Sailing Ship and recalls drowning in the cold sea, and later, in another life, he recalls serving as a Solider in the First World War, and so is able to theorise how, when the time comes, one can cheat Death. ..

No society can escape population ageing. This demographic phenomenon has profound social consequences on the lifestyles of individuals and societies. In the light of the accelerated ageing of the Mediterranean area, the analyses which inform this work aim to understand how the age-related policies of Nation-States are partly responsible for the behaviours of the generations. They also highlight how the lifestyle changes are the result of trends which are common to these societies. The Mediterranean area constructed here by the researchers offers an in-depth reflection on the national cases presented, in terms of their specificities or societal singularities, as well as of their dynamics of convergence. Drawing on empirical research in sociology, demography, geography and economics, exploiting the most recent data available and setting the present in historical perspective, Ageing, Lifestyles and Economic Crises studies Mediterranean societies in relation to three major challenges which they now confront. These are: population ageing and its implications in terms of intergenerational family support relationships; increasingly insecure adult professional trajectories and their consequences for the evolution of social gender roles, in an economic context commonly referred to as a 'crisis'; and lastly the role of Nation-States' public policies in the social reproduction of these gender inequalities. These three issues are the keystone to understanding the ongoing transformations in the lifestyles and life cycles of Mediterranean societies. This volume marshals a wealth of recent data that will be useful not only to many academics and scientists but also to local and national policy-makers.

The military toll of World War I is widely known: millions of Britons were mobilised, many thousands killed or wounded, and the landscape of British society changed forever. But how was the conflict experienced by the people of Surrey on the home front? Surrey Heritage's project Surrey in the Great War: A County Remembers has, over the four-year centenary commemoration, explored the wartime stories of Surrey's people and places. The project's discoveries are here captured through text, case studies and images. This book chronicles the mobilisation of Surrey men, the training of foreign troops in the county, objection to military service, defence against invasion, voluntary work and fundraising, the experiences of women and children, shortages, industrial supply to the armed forces and the commemoration of Surrey's dead. Drawing heavily on the rich archives of Surrey Heritage, it is an engaging exploration of a county in the shadow of the first globalised war between industrialised nations.

In Tumor Targeting in Cancer Therapy, Dr. Michel Page and a panel of authoritative experts from the drug industry, clinics, and academia introduce the principles and techniques of tumor targeting and critically survey their applications from laboratory to bedside. By concisely synthesizing the many technical details, the authors illuminate this innovative technique, ranging from the fundamentals of drug targeting and in vivo and in vitro experimentation, to such emerging therapeutic uses as radioimmunotherapy, radioimmunodetection, therapy with cytotoxic antibodies, immunotoxins, enzyme prodrug immunotherapy, and immunotherapeutics with fusion proteins. There are also reviews of targeting tumors with radioimmunoconjugates, photodynamic therapy, and magnetic drugs, as well as discussions of the internalization of antibodies, bioconjugation and biodistribution, the use of cytotoxic drugs, and the pros and cons of targeting by antibody or ligand.