This handbook provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ("the glycome"). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans.
* Synthesizes contributions from experts in biology, chemistry, bioinformatics, biotechnology, and medicine
* Highlights chapters devoted to chemical synthesis, cancer glycomics and immune cell glycomics
* Includes discussions of proteomics, mass spectrometry, NMR, array technology, and transcriptomics analytic approaches

Exploring writing of working-class Dublin after Sean O'Casey, this book breaks new ground in Irish Studies, unearthing submerged narratives of class in Irish life. Examining how working-class identity is depicted by authors like Brendan Behan and Roddy Doyle, it discusses how this hidden, urban Ireland has appeared in the country's literature.

This book provides scholarly perspectives on a range of timely concerns in Irish diaspora studies. It offers a focal point for fresh interchanges and theoretical insights on questions of identity, Irishness, historiography and the academy's role in all of these. In doing so, it chimes with the significant public debates on Irish and Irish emigrant identities that have emerged from Ireland's The Gathering initiative (2013) and that continue to reverberate throughout the Decade of Centenaries (2012-2023) in Ireland, North and South. In ten chapters of new research on key areas of concern in this field, the book sustains a conversation centred on three core questions: what is diaspora in the Irish context and who does it include/exclude? What is the view of Ireland and Northern Ireland from the diaspora? How can new perspectives in the academy engage with a more rigorous and probing theorisation of these concerns? This thought-provoking work will appeal to students and scholars of history, geography, literature, sociology, tourism studies and Irish studies.

What can culture, and its manifestations in artistic and creative forms, 'do'? Creativity and resistance in a hostile world draws on original collaborative research that brings together a range of stories and perspectives on the role of creativity and resistance in a hostile world. In times of racial nationalism across the world, this volume seeks to understand how creative acts have agitated for social change. The book suggests that creative actions themselves, and acting together creatively, can at the same time offer vital sources of hope. Drawing on a series of case studies, this volume focuses on the past and emergent grassroots arts work that has responded to racisms, the legacies of colonialism or the depredations of capitalist employment across several contexts and locations, including England, Northern Ireland and India. The book makes a timely intervention, foregrounding the value of creativity for those who are commonly marginalised from centres of power, including from the mainstream cultural industries. The authors also critically reflect on the possibilities and limitations of collaborative research within and beyond the academy. -- .

First published in 2000. Routledge is an imprint of Taylor & Francis, an informa company.

Previous research on this topic has not focused on nutrition-specific social support for elderly women. This unique study seeks to describe and explore the current situation in a group of elderly women living alone in government subsidized housing.

What can culture, and its manifestations in artistic and creative forms, 'do'? Creativity and resistance in a hostile world draws on original collaborative research that brings together a range of stories and perspectives on the role of creativity and resistance in a hostile world. In times of racial nationalism across the world, this volume seeks to understand how creative acts have agitated for social change. The book suggests that creative actions themselves, and acting together creatively, can at the same time offer vital sources of hope. Drawing on a series of case studies, this volume focuses on the past and emergent grassroots arts work that has responded to racisms, the legacies of colonialism or the depredations of capitalist employment across several contexts and locations, including England, Northern Ireland and India. The book makes a timely intervention, foregrounding the value of creativity for those who are commonly marginalised from centres of power, including from the mainstream cultural industries. The authors also critically reflect on the possibilities and limitations of collaborative research within and beyond the academy. -- .

This book provides scholarly perspectives on a range of timely concerns in Irish diaspora studies. It offers a focal point for fresh interchanges and theoretical insights on questions of identity, Irishness, historiography and the academy's role in all of these. In doing so, it chimes with the significant public debates on Irish and Irish emigrant identities that have emerged from Ireland's The Gathering initiative (2013) and that continue to reverberate throughout the Decade of Centenaries (2012-2023) in Ireland, North and South. In ten chapters of new research on key areas of concern in this field, the book sustains a conversation centred on three core questions: what is diaspora in the Irish context and who does it include/exclude? What is the view of Ireland and Northern Ireland from the diaspora? How can new perspectives in the academy engage with a more rigorous and probing theorisation of these concerns? This thought-provoking work will appeal to students and scholars of history, geography, literature, sociology, tourism studies and Irish studies.

A History of Irish Working-Class Writing provides a wide-ranging and authoritative chronicle of the writing of Irish working-class experience. Ground-breaking in scholarship and comprehensive in scope, it is a major intervention in Irish Studies scholarship, charting representations of Irish working-class life from eighteenth-century rhymes and songs to the novels, plays and poetry of working-class experience in contemporary Ireland. There are few narrative accounts of Irish radicalism, and even fewer that engage 'history from below'. This book provides original insights in these relatively untilled fields. Exploring workers' experiences in various literary forms, from early to late capitalism, the twenty-two chapters make this book an authoritative and substantial contribution to Irish studies and English literary studies generally.

Race, Labor, and Violence in the Delta examines the history of labor relations and racial conflict in the Mississippi Valley from the Civil War into the late twentieth century. This essay collection grew out of a conference marking the hundredth anniversary of one of the nation's deadliest labor conflicts-the 1919 Elaine Massacre, during which white mobs ruthlessly slaughtered over two hundred African Americans across Phillips County, Arkansas, in response to a meeting of unionized Black sharecroppers. The essays here demonstrate that the brutality that unfolded in Phillips County was characteristic of the culture of race- and labor-based violence that prevailed in the century after the Civil War. They detail how Delta landowners began seeking cheap labor as soon as the slave system ended-securing a workforce by inflicting racial terror, eroding the Reconstruction Amendments in the courts, and obstructing federal financial-relief efforts. The result was a system of peonage that continued to exploit Blacks and poor whites for their labor, sometimes fatally. In response, laborers devised their own methods for sustaining themselves and their communities: forming unions, calling strikes, relocating, and occasionally operating outside the law. By shedding light on the broader context of the Elaine Massacre, Race, Labor, and Violence in the Delta reveals that the fight against white supremacy in the Delta was necessarily a fight for better working conditions, fair labor practices, and economic justice.

Historians have typically thought of Populism as a radical agrarian movement. In this much-needed corrective, Pierce argues that, in Ohio, Populism was an urban, not rural, movement and that industrial workers and trade unionists formed the core of the People's (or Populist) party. Through case studies of Cleveland, Cincinnati, and Columbus, Pierce examines the efforts of Ohio unions--especially the United Mine Workers --to protect the rights of workers, curb the abuses of corporations, and reform the state's and nation's government through an alliance with the People's party.Striking with the Ballot focuses on the Crisis of the 1890s: when the Panic of 1893, the Pullman strike and boycott, the arrest of Debs, Coxey's march, and the failure of the nationwide coal strike threw the country into disarray. Pierce demonstrates that trade unionists in Ohio, and throughout the Industrial Midwest, responded by mobilizing politically under the banner of the People's party. Support for the People's party was so strong among the nation's trade unionists that Ohio's leading Populist, John McBride, won the presidency of the American Federation of Labor in 1894. Ohio labor's reform agenda survived the subsequent collapse of the People's party and informed labor's political activity through the Progressive era. Pierce offers a provocative new narrative for those interested in labor history, Populism, Progressivism, and Ohio history.

Van Tine and Pierces "Builders of Ohio is composed of twenty-four essays that use biography to explore Ohio's history. Collectively, they provide a historical overview of the state's development from George Croghan's search for fame and fortune on the seventeenth-century frontier through Dave Thomas's more recent creation of a fast-food empire. Each chapter also addresses important events and transformations in the state's history such as: European settlement; Native American resistance; the creation of territorial and state governments; the development of the state's educational and economic institutions; the disruption created by the Civil War; the struggle of African Americans and women to participate in Ohio's public life; efforts to ameliorate the pernicious effects of industrialization; the negotiation of the state's role in a nation increasingly dominated by the federal government; or the ramifications of de-industrialization and rise of a service economy.