Current Controversies in Perinatology is covered in this issue of Clinics in Perinatology, guest edited by Drs. Michael Uhing and Robert Kliegman. Authorities in the field have come together to pen articles on Strategies to prevent bacterial and fungal infection in the NICU, Drugs of choice for sedation and analgesia in the NICU, Iron therapy for preterm infants, Management of fetal arrhythmias, Inhaled nitric oxide for preterm infants, Racial disparity in low birth weight and infant mortality, Evaluation and treatment of hypotension in the preterm infant, Indications for home apnea monitoring, Short bowel syndrome: how short is too short?, Anemia in the preterm infant: the role of transfusions and erythropoietin, Evaluation and management of stroke in the neonate, Screening for postpartum depression in the NICU, Treatment of gastroesophageal reflux in the preterm and term infant, Optimizing growth in the preterm infant, The role of postnatal steroids in the treatment of bronchopulmonary dysplasia, and The role of genomics in the NICU.