Cosmetics are the most widely applied products to the skin and include creams, lotions, gels and sprays. Their formulation, design and manufacturing ranges from large cosmetic houses to small private companies. This book covers the current science in the formulations of cosmetics applied to the skin. It includes basic formulation, skin science, advanced formulation, and cosmetic product development, including both descriptive and mechanistic content with an emphasis on practical aspects. Key Features: Covers cosmetic products/formulation from theory to practice Includes case studies to illustrate real-life formulation development and problem solving Offers a practical, user-friendly approach, relying on the work of recognized experts in the field Provides insights into the future directions in cosmetic product development Presents basic formulation, skin science, advanced formulation and cosmetic product development

This two volume Second Edition describes the anatomical, physiological, pharmaceutical, and technological aspects of delivery routes, found in areas like:

• Oral
• Ocular
• Dermal and transdermal
• Vaginal
• Colonic
• Oral mucosal
• Nasal
• Pulmonary

Providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value, topics include:

• Intellectual property rights and regulatory issues and challenges
• osmotic systems and Qtrol. Qdis. Matrix Systems
• thiolated polymers for CR, Oradur. IDD technology, and chronotherapy technology
• Oral-lyn (RapidMist Technology)
• Dentipatch drug delivery system
• ORAVESCENT: a novel technology for the transmucosal delivery of drugs
• Egalet and COLAL technologies

Recent advances in our understanding of the development and morphology of normal skin have led to improved methods to deliver therapeutic compounds to selected targeted areas both within the skin and systemically. This reference provides a clear overview of pharmaceutical and cosmetic practices, drugs, and therapies to manage and treat major and minor skin disorders. Written for scientists interested in dermatological therapy and marketers of pharmaceutical and cosmetic products, the text is also useful for students developing strong research methods. The book covers drugs used to manage a range of skin disorders and the site where the effect is sought. It examines the efficiency and delivery of topical therapies, including various pharmaceutical therapies. It also explains how percutaneous absorption is affected by age, skin, site, race, skin disease, and damage and product form. Particular emphasis is on novel treatment approaches for major skin diseases and injuries pertaining to wounds and burns.

This two volume Second Edition describes the anatomical, physiological, pharmaceutical, and technological aspects of delivery routes, found in areas like: Oral Ocular Dermal and transdermal Vaginal Colonic Oral mucosal Nasal Pulmonary Providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value, topics include: modified drug release landscape; academic, regulatory, and intellectual property viewpoints I-vation Sustained Release Intravitreal System ViaNase Intranasal Device and controlled particle dispersion technology Platform Microneedles for drug delivery, PassPort system, Dot-Matrix technology, ultrasound, iontophoretic and technologies, DiretcHaler Nasal technology, intravaginal ring systems, Supravail, Vagisite, C-Vad (TM) Vaginal Insert, and 'Smart' Vaginal Delivery Systems the AERx (R) Pulmonary Drug Delivery System AAD-Adaptive aerosol delivery technology nebulizer technologies and dry powder inhaler systems

The source Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin absorption and the various governmental and industrial programs concerned with skin permeation and toxicity. These include alternative in silico, in vitro, and in vivo strategies to conduct studies for regulatory requirements. To make room for this new expanded content, the editors are publishing a concurrent text entitled: Dermatological and Cosmetic Development with a concentration on subjects concerned with dermatological and cosmetic therapies

Cosmetics are the most widely applied products to the skin and include creams, lotions, gels and sprays. Their formulation, design and manufacturing ranges from large cosmetic houses to small private companies. This book covers the current science in the formulations of cosmetics applied to the skin. It includes basic formulation, skin science, advanced formulation, and cosmetic product development, including both descriptive and mechanistic content with an emphasis on practical aspects. Key Features: Covers cosmetic products/formulation from theory to practice Includes case studies to illustrate real-life formulation development and problem solving Offers a practical, user-friendly approach, relying on the work of recognized experts in the field Provides insights into the future directions in cosmetic product development Presents basic formulation, skin science, advanced formulation and cosmetic product development

This is a 2 volume set. Volume 1 is Dermatological and Cosmeceutical Development: Absorption Efficacy and Toxicity. Recent advances in our understanding of the development and morphology of normal skin has led to improved methods to deliver therapeutic compounds to selected targeted areas both within the skin and systemically. This reference provides a clear overview of current pharmaceutical and cosmetic practices in the management of both major and minor skin disorders, and provides an expansive overview of novel drugs and therapies used to treat these conditions. Written for scientists interested in dermatological therapy and those concerned with the marketing for pharmaceutical and cosmetic products, this text will also prove useful for students developing strong research methods. Volume 2 is Dermal Absorption and Toxicity Assessment, Second Edition The book Dermal Absorption and Toxicity Assessment supplies a state-of-the-art overview of the dermal absorption process, and is divided into six well organized sections. Written by internationally recognized experts in the field, this Second Edition is a complete revised and updated text, covering the wide range of methods used to assess skin absorption and the various governmental and industrial programs concerned with skin permeation and toxicity. These include alternative in silico, in vitro, and in vivo strategies to conduct studies for regulatory requirements. To make room for this new expanded content, the editors are publishing a concurrent text entitled: Dermatological and Cosmetic Development with a concentration on subjects concerned with dermatological and cosmetic therapies. Dermal Absorption and Toxicity and Assessment is a completely revised and updated text expanded to include coverage pertaining to innovative research...expands on the specific barrier properties of the skin such as its physical structure, biosensor properties, cutaneous metabolism, skin lipid morphology, and dermal blood and lymphatic flow, examines both the standard established laboratory techniques, for example, diffusion cell technology, and also covers new techniques like cultured skin equivalents, dermal absorption, and risk assessment

Because of the slow and costly process of developing new blockbuster drugs, pharmaceutical scientists are increasingly charged with reformulating existing drugs in order to expand a company's market opportunity and to sustain company growth. This presents an opportunity for formulation scientists to innovate and develop novel drug delivery systems to extend the commercial life of existing drugs. Divided into two volumes, this "Second Edition" describes the anatomical, physiological, pharmaceutical, and technological aspects of oral, colonic and rectal, ocular, oral mucosal, dermal and transdermal, nasal, vaginal, and pulmonary delivery routes, providing insight and critical assessment of the many available and emerging modified release drug delivery systems for their current and future value.

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