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With their best-selling astronomy textbook, HORIZONS, International
Edition authors Mike Seeds and Dana Backman help you understand
your place in the universe--not just your location in space but
your role in the unfolding history of the physical universe. To
achieve this goal, they focuses on two central questions: "What Are
We?" which highlights your place as a planet dweller in an evolving
universe, guiding you to better understand where we came from and
how we formed; and "How Do We Know?" which provides insights into
how the process of science can teach us more about what we are.
Since the discovery of the pharmacological and toxicological
importance of inhibiting the cyclooxygenase (COX) enzymes by
non-steroidal anti-inflammatory drugs (NSAIDs), much research has
gone into the development of methods to study the biological
functions of COX-1 and COX-2. In Cyclooxygenases: Methods and
Protocols, experts and pioneers in the field present the most
up-to-date in vitro and in vivo techniques routinely used in COX
research. The volume delves into essential topics such as the
purification, cloning, and expression of COX enzymes as well as in
vitro assays aimed at determining the inhibitory potency of drugs
on COX-1 and COX-2 activities, with chapters describing protocols
used for the extraction and measurement of the prostanoids. This
volume also describes in vivo disease models used to study the
roles of COX-1 and COX-2 in gastrointestinal injury, inflammation,
and pain. As a book in the highly successful Methods in Molecular
Biology (TM) series, the protocols chapters include brief
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and notes on troubleshooting and avoiding
known pitfalls. Authoritative and cutting-edge, Cyclooxygenases:
Methods and Protocols serves as an indispensable tool for all
scientists seeking the treatment of inflammation, pain, fever, and
other harmful conditions.
Fascinating, engaging and extremely visual, FOUNDATIONS OF
ASTRONOMY, 14th Edition, is renowned for its current coverage,
reader-friendly presentation and detailed--yet clear--explanations.
The authors' goals are to help you use Astronomy to understand
science, and use science to answer two fundamental questions: What
are we? And how do we know? Available with WebAssign, the powerful
digital solution that enriches the teaching and learning
experience. Complete with practice opportunities, a wealth of
supplemental resources and immediate feedback, you'll be set up to
succeed.
Since the discovery of the pharmacological and toxicological
importance of inhibiting the cyclooxygenase (COX) enzymes by
non-steroidal anti-inflammatory drugs (NSAIDs), much research has
gone into the development of methods to study the biological
functions of COX-1 and COX-2. In Cyclooxygenases: Methods and
Protocols, experts and pioneers in the field present the most
up-to-date in vitro and in vivo techniques routinely used in COX
research. The volume delves into essential topics such as the
purification, cloning, and expression of COX enzymes as well as in
vitro assays aimed at determining the inhibitory potency of drugs
on COX-1 and COX-2 activities, with chapters describing protocols
used for the extraction and measurement of the prostanoids. This
volume also describes in vivo disease models used to study the
roles of COX-1 and COX-2 in gastrointestinal injury, inflammation,
and pain. As a book in the highly successful Methods in Molecular
Biology (TM) series, the protocols chapters include brief
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and notes on troubleshooting and avoiding
known pitfalls. Authoritative and cutting-edge, Cyclooxygenases:
Methods and Protocols serves as an indispensable tool for all
scientists seeking the treatment of inflammation, pain, fever, and
other harmful conditions.
Focusing on two central questions -- "What are we?" and "How Do We
Know?" -- HORIZONS: EXPLORING THE UNIVERSE, 14th Edition, helps you
understand our place in the universe and how scientists work.
Chapter-opening "Guideposts" and a conversational writing style
make the content accessible and help you acquire an understanding
of the universe (rather than just memorize basic facts); and online
resources let you study where and when you want, to best meet your
individual learning style.
Fascinating, engaging and extremely visual, STARS AND GALAXIES,
10th Edition, is renowned for its current coverage, reader-friendly
presentation and detailed--yet clear--explanations. The authors'
goals are to help you use Astronomy to understand science, and use
science to answer two fundamental questions: What are we? And how
do we know? Available with WebAssign, the powerful digital solution
that enriches the teaching and learning experience. It includes
Virtual Astronomy Labs 3.0--a set of 20 interactive activities that
combine analysis of real astronomical data with robust
simulations--providing a true online laboratory experience for your
Introductory Astronomy course.
Michael Seed should have had what every child deserves: love, care
and attention, and the chance to be just what he was - an innocent
young boy. Instead, Michael's formative years were filled with
unspeakable neglect, misery and abuse from an alcoholic father who
robbed him of his childhood and drove his mother to suicide. One
horrific night, Michael realized that the situation was escalating
as his father began the sexual abuse that would continue for years.
School offered no reprieve as Michael encountered terrible bullying
and a teacher who repeatedly violated him. It seemed he was
destined for a life of inescapable misery. Despite everything,
Michael was ultimately saved by his own will to live and by the
books that inspired him to move on and seek a better life. After
years of silence, Michael is ready to tell his story, a story that,
though shockingly painful, is a testament to his remarkable ability
to triumph in the face of the most appalling circumstances and to
escape the horrors of his past.
Father Michael Seed has been at the privileged center of events for
a quarter of a century, and has played a uniquely influential role.
In this explosive memoir Britain's "priest to the stars" covers his
encounters with some of the most prominent political and public
figures of a generation, and gives a rare and fascinating glimpse
of behind-the-scenes events in the corridors of power. His
remarkable disclosures of life at the top, in parliament, palace,
and church, are revealed through a series of hilarious anecdotes
that will have readres laughing out loud. For years he secretly
gave Mass to the Blairs in Dowing Street, initially slipping in
through a rear, ground floor window, before it was leaked to the
press in 2006. His has been a turbulent ride through life,
denounced and envied by those who dislike his champagne style of
Catholicism, loved by those who declare him a saint, and so admired
by the "Times" that it demanded he be instantly made a bishop. His
friendship with people like best chum Ann Widdecombe, Alan Clark,
the Dutchess of Argyll, Lord Longford, George Carman QC, John Paul
Getty, the Duke of Norfolk, a host of royals, and half a dozen
prime ministers, has left little room for dullness. His insights
into life in Westminster Cathedral and with Cardinal Basil Hume
make all religion-based television sitcoms seem deadly boring by
comparison with the real thing.
Fascinating, engaging, and extremely visual, FOUNDATIONS OF
ASTRONOMY, Thirteenth Edition, is renowned for its current
coverage, reader-friendly presentation, and detailed, yet clear
explanations. The authors' goals are to help you use astronomy to
understand science--and use science to answer two fundamental
questions: What are we? And how do we know?
With this revised edition of THE SOLAR SYSTEM, author Mike Seeds'
goal is to help you use astronomy to understand science -- and use
science to understand what we are. Fascinating and engaging, this
text will help you answer two fundamental questions: What are we?
How do we know? Crafting a story about astronomy, Seeds shows you
how to ask questions to gradually puzzle out the beautiful secrets
of the physical world and our place in it. This edition addresses
the newest developments and latest discoveries in the exciting
study of astronomy, including new data on Jupiter's ring system;
new observations of the shapes of stars; new evidence of dark
energy, quasars, and galaxy collisions; and a look inside supernova
explosions.
Fascinating, engaging and extremely visual,THE SOLAR SYSTEM, 10th
Edition, is renowned for its current coverage, reader-friendly
presentation and detailed--yet clear--explanations. The authors'
goals are to help you use Astronomy to understand science, and use
science to answer two fundamental questions: What are we? And how
do we know? Available with WebAssign, the powerful digital solution
that enriches the teaching and learning experience. It includes
Virtual Astronomy Labs 3.0--a set of 20 interactive activities that
combine analysis of real astronomical data with robust
simulations--providing a true online laboratory experience for your
Introductory Astronomy course.
Fascinating, engaging, and extremely visual, FOUNDATIONS OF
ASTRONOMY, Enhanced Thirteenth Edition, is renowned for its current
coverage, reader-friendly presentation, and detailed, yet clear
explanations. The authors' goals are to help you use astronomy to
understand science—and use science to answer two fundamental
questions: What are we? And how do we know?
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