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This unique introductory text explains cell functions using the
engineering principles of robust devices. Adopting a process-based
approach to understanding cell and tissue biology, it describes the
molecular and mechanical features that enable the cell to be robust
in operating its various components, and explores the ways in which
molecular modules respond to environmental signals to execute
complex functions. The design and operation of a variety of complex
functions are covered, including engineering lipid bilayers to
provide fluid boundaries and mechanical controls, adjusting cell
shape and forces with dynamic filament networks, and DNA packaging
for information retrieval and propagation. Numerous problems, case
studies and application examples help readers connect theory with
practice, and solutions for instructors and videos of lectures
accompany the book online. Assuming only basic mathematical
knowledge, this is an invaluable resource for graduate and senior
undergraduate students taking single-semester courses in cell
mechanics, biophysics and cell biology.
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