Micro and Nano Flow Systems for Bioanalysis addresses the latest developments in biomedical engineering at very small scales. It shows how organic systems require multi-scale understanding in the broadest sensewhether the approach is experimental or mathematical, and whether the physiological state is healthy or diseased. Micro-and nano-fluidics represent key areas of translational research in which state-of-the-art engineering processes and devices are applied to bedside monitoring and treatment. By applying conventional micro- and nano-engineering to complex organic solids, fluids, and their interactions, leading researchers from throughout the world describe methods and techniques with great potential for use in medicine and clinical practice. Coverage includes the seeming plethora of new, fine-scale optical methods for measuring blood flow as well as endothelial activation and interaction with tissue. Generic areas of modeling and bioelectronics are also considered. In keeping with the recurring theme of medicine and clinical practice, approximately half of the chapters focus on the specific application of micro- and nano- flow systems to the understanding and treatment of cancer and cardiovascular diseases. This book developed from an Expert Overview Session on "Micro & Nano Flows in Medicine: the way ahead" at the 3rd Micro and Nano Flows Conference (MNF2011) held in Thessaloniki, Greece. Additional chapters were included to enhance the international, state-of-the-art coverage.

Medical consensus once held that all concussions were the same, and treatment for all concussion patients therefore followed the same standard approach. In this volume, Anthony Kontos and Michael Collins debunk the one-size-fits-all approach, arguing instead that individuals who experience concussion respond best to targeted interventions based on their specific clinical profile of symptoms and impairment. In fact, the most commonly prescribed management strategy-rest-can actually prolong recovery time for some individuals. The authors present a comprehensive, team-based model for assessment and treatment of concussion. Assessment should involve an interdisciplinary lineup that evaluates the patient across multiple domains, including vestibular and oculomotor function, cognitive fatigue, post-traumatic migraine, and anxiety/mood. Based on the individual's clinical profile, treatment should actively target the affected domains. The book combines empirical evidence with case examples, with special attention to at-risk populations such as athletes, military, and youth. This resource is essential reading for those who assess, treat, or research concussion, including professionals and students in clinical-counseling psychology, neuropsychology, neurology, neurosurgery, optometry, pediatrics, physical therapy, primary care, sports medicine, and athletic training.