A definitive history of mescaline that explores its mind-altering effects across cultures, from ancient America to Western modernity Mescaline became a popular sensation in the mid-twentieth century through Aldous Huxley's The Doors of Perception, after which the word "psychedelic" was coined to describe it. Its story, however, extends deep into prehistory: the earliest Andean cultures depicted mescaline-containing cacti in their temples. Mescaline was isolated in 1897 from the peyote cactus, first encountered by Europeans during the Spanish conquest of Mexico. During the twentieth century it was used by psychologists investigating the secrets of consciousness, spiritual seekers from Aleister Crowley to the president of the Church of Jesus Christ of Latter-day Saints, artists exploring the creative process, and psychiatrists looking to cure schizophrenia. Meanwhile peyote played a vital role in preserving and shaping Native American identity. Drawing on botany, pharmacology, ethnography, and the mind sciences and examining the mescaline experiences of figures from William James to Walter Benjamin to Hunter S. Thompson, this is an enthralling narrative of mescaline's many lives.

This is the true story of Colonel Edward Marcus Despard, the character in the fifth series of the BBC's popular television drama Poldark. Colonel Despard was the last person to be sentenced to hanging, drawing and quartering in Britain - for high treason, an alleged plot to kill the king. His execution on 21st February 1803 was witnessed by twenty thousand hushed onlookers. Their silence was ominous, for few believed he was guilty. His death would tear apart a Britain still reeling from the impact of the French Revolution and the Napoleonic Wars. But who was Edward Marcus Despard? Was he, as his comrade-in-arms on the Spanish Main Lord Nelson believed, an outstanding British army officer of unimpeachable honour, courage and patriotism? Or, as the white slave-owners of the Caribbean claimed, a traitor not only to his nation but to his race, who had married a local woman and championed the rights of freed slaves? And when Despard returned to London to answer these allegations, did he commit himself to the cause of political reform in Britain's best interest? Or did he join a shadowy international terrorist conspiracy dedicated to the murder of George III and the overthrow of the state? Despard's contested fate marked the sensational climax to a British revolution that never happened, but it also presaged the birth of modern democracy. 'Compelling, absorbing and wide-ranging . . . Jay weaves a complex variety of themes, many with overtly topical resonances, into Despard's journey from hero to traitor' Sunday Times

Is mental illness - or madness - at root an illness of the body, a disease of the mind, or a sickness of the soul? Should those who suffer from it be secluded from society or integrated more fully into it? This Way Madness Lies explores the meaning of mental illness through the successive incarnations of the institution that defined it: the madhouse, designed to segregate its inmates from society; the lunatic asylum, which intended to restore the reason of sufferers by humane treatment; and the mental hospital, which reduced their conditions to diseases of the brain. Moving and sometimes provocative illustrations and photographs, sourced from the Wellcome Collection's extensive archives and the archives of mental institutions in Europe and the U.S., illuminate and reinforce the compelling narrative, while extensive `gallery' sections present revealing and thought-provoking artworks by asylum patients and other artists from each era of the institution and beyond.

This is the remarkable story of James Lee who, starting in 1895, spent 20 years pursuing all the pleasures and dangers that the Far East had to offer. A twilight world of ports, red light districts, drug dens and secret chambers of vice from Aden to Kyoto

'This is the story of how I came to drill a hole in my head to get permanently high...' Joey Mellen's memoir has achieved a legendary status that reaches far beyond the 500 long-vanished copies he printed in 1970. It has been hailed as the blueprint for the next step in human evolution, denounced as a tragic example of the dangers of drug experimentation, and retold endlessly as an irresistible anecdote of high craziness. A heavily expanded edition of Joe Mellen's legendary, long out-of-print auto-trepanation memoir.

Intriguing Asian thriller with close interaction between the principal characters who are caught up in a cunning extradition of deceipt and kidnap amongst Triad and ex-Triad members.