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This book allows readers to gain an in-depth understanding of the
role of real-world data in pharmacoepidemiology, and highlights the
strengths and limitations of the respective databases with regard
to pharmacoepidemiological research. Over the past decade, the
increasing use of real-world data in pharmacoepidemiological
research has been accompanied by a growing recognition of the value
of real-world evidence in clinical and regulatory decision-making.
Electronic healthcare databases allow analyses of drug and vaccine
utilization in routine care after approval, as well as
investigations of their comparative effectiveness and safety. They
are especially useful for the identification of rare risks and rare
drug exposures over long periods of time, and as such sustainably
extend the basis for drug safety research. This book provides an
introduction to the role of real-world data in
pharmacoepidemiological research and the main developments in the
last 15 years. It also offers a comprehensive overview of the
general classification characteristics of databases, together with
their strengths and limitations, and a detailed description of 21
individual databases, written by professionals who work with or
maintain them.
This book allows readers to gain an in-depth understanding of the
role of real-world data in pharmacoepidemiology, and highlights the
strengths and limitations of the respective databases with regard
to pharmacoepidemiological research. Over the past decade, the
increasing use of real-world data in pharmacoepidemiological
research has been accompanied by a growing recognition of the value
of real-world evidence in clinical and regulatory decision-making.
Electronic healthcare databases allow analyses of drug and vaccine
utilization in routine care after approval, as well as
investigations of their comparative effectiveness and safety. They
are especially useful for the identification of rare risks and rare
drug exposures over long periods of time, and as such sustainably
extend the basis for drug safety research. This book provides an
introduction to the role of real-world data in
pharmacoepidemiological research and the main developments in the
last 15 years. It also offers a comprehensive overview of the
general classification characteristics of databases, together with
their strengths and limitations, and a detailed description of 21
individual databases, written by professionals who work with or
maintain them.
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