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The overuse, misuse and widespread prophylactic application of
antibiotics led to the emergence of drug resistant micro-organisms
and also disturb the beneficial microflora (Lactobacilli) of the
body. Probiotics are live microorganisms, which, when administered
in an adequate amount, confer a health benefit on the host. The
most common probiotic strains belong to the genera Lactobacilli and
Bifidobacterium. The purpose of the present study was to evaluate
the effect of probiotic (Inersan lozenges - Lactobacillus brevis)
alone, combination of probiotic with doxycycline and doxycycline
alone on aggressive periodontitis, it being both a clinical and
microbiological study. Probiotic has a future in the treatment of
aggressive periodontitis, as most of the time, antibiotics are
prescribed. These antibiotics can lead to the emergence of drug
resistant micro-organisms and also disturb the beneficial
microflora of the body. Thus, as an alternative to antibiotics,
probiotics can be used as they repopulate beneficial microflora and
reduce the pathogenic bacteria.
Attitudes have changed dramatically over the last few years. Both
patients and practitioners want to know more about the treatments
given and the agents that put them at risk of disease. Will a
treatment work? Is this the best available treatment? Can anything
be done to prevent a particular disease? The ability to answer
these questions is inherently dependent upon the ability to read
and interpret the dental literature. This is why it has become
increasingly important for students and practitioners to be
proficient in the area of evidence based dentistry and critical
appraisal. The purpose of this book is to allow periodontists to
gain confidence in their own ability to assess research reports and
overcome the misconception.
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