Probiotics in The Prevention and Management of Human Diseases: A Scientific Perspective addresses the use of probiotics and their mechanistic aspects in diverse human diseases. In particular, the mechanistic aspects of how these probiotics are involved in mitigating disease symptoms (novel approaches and immune-mechanisms induced by Probiotics), clinical trials of certain probiotics, and animal model studies will be presented through this book. In addition, the book covers the role of probiotics in prevention and management aspects of crucial human diseases, including multidrug resistant infections, hospital acquired infections, allergic conditions, autoimmune diseases, metabolic disorders, gastrointestinal diseases, neurological disorders, and cancers. Finally, the book addresses the use of probiotics as vaccine adjuvants and as a solution for nutritional health problems and describes the challenges of using probiotics in management of human disease conditions as well as their biosafety concerns. Intended for nutrition researchers, microbiologists, physiologists, and researchers in related disciplines as well as students studying these topics require a resource that addresses the specific role of probiotics in the prevention and management of human disease.

Advances in Trichoderma Biology for Agricultural Applications covers the beneficial properties of Trichoderma in enhancing global agricultural productivity. Trichoderma are biotechnologically significant fungi, being widely used both agriculturally and industrially. In many cases Trichoderma are also a potential drug source of clinical importance. In recent years, driven by advances in genetics and genomics, research on these fungi has opened new avenues for its various applications. This book covers i) Current state of Trichoderma taxonomy, and species identification, ii) Trichoderma and plant-pathogenic fungi interactions, iii) Trichoderma interactions with plants, including rhizosphere competence of Trichoderma, antagonistic potentials, plant growth promotion, and management of various abiotic stresses in plants, iv) Practical aspects of Trichoderma commercialization in agriculture, v) Biosynthesis of metal-based nanoparticles and its application, and vi) Negative impact of Trichoderma strains in the environments. Reading this book should kindle further discussions among researchers working in fungal biotechnology, microbiology, agriculture, environmental science, forestry, and other allied subjects and thus lead to a broader scope of Trichoderma-based products and technologies. The knowledge shared in this book should also provide a warning on the potential risks associated with Trichoderma.

This volume provides basic insight and protocols relating to endophytic microbes. Chapter are divided into five major sections detailing basic isolation, bioactive metabolites production. endophytism, isolation and identification of endophytes, bioactive potentials, and screening of metabolites. Authoritative and cutting-edge, Endophytic Microbes: Isolation, Identification, and Bioactive Potentials aims to provide comprehensive and accessible methods to undergraduate, graduate, and established scientist.

This volume provides methods on procedures for assessing the biosafety aspects of probiotics. Chapters are divided into five parts detailing in vitro biosafety assessment, biogenic amine production, D-lactic acid production, toxin production, production of various enzymes, determination of toxicity, mutagenicity, virulence genes, capsule formation, hemolytic activity, DNAse activity, bile salt deconjugation, antibiotic resistance, antibiotic resistance gene transfer, mucin degradation, platelet aggregation, and in vivo biosafety assessment of probiotics including determination of infectivity, reproductive and developmental toxicity, and evaluation of immunological parameters in animal models. Authoritative and cutting-edge, Biosafety Assessment of Probiotic Potential aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.